Long-term effects of growth hormone (GH) on body fluid distribution in GH deficient adults: a four months double blind placebo controlled trial

Sidse Fisker; A M Rosenfalck; E Frandsen; J O Jørgensen; J Hilsted; J S Christiansen

Long-term effects of growth hormone (GH) on body fluid distribution in GH deficient adults: a four months double blind placebo controlled trial

Sidse Fisker, A M Rosenfalck, E Frandsen, J O Jørgensen, J Hilsted, J S Christiansen

20 Citations (Scopus)

Abstract

Short-term growth hormone (GH) treatment normalises body fluid distribution in adult GH deficient patients, but the impact of long-term treatment on body fluid homeostasis has hitherto not been thoroughly examined in placebo controlled trials. To investigate if the water retaining effect of GH persists for a longer time we examined the impact of 4 months GH treatment on extracellular volume (ECV) and plasma volume (PV) in GH deficient adults.

Original language	English
Journal	European journal of endocrinology / European Federation of Endocrine Societies
Volume	140
Issue number	1
Pages (from-to)	11-6
Number of pages	6
ISSN	0804-4643
Publication status	Published - Jan 1999
Externally published	Yes

Keywords

Adult
Blood Pressure
Body Composition
Body Fluids
Double-Blind Method
Extracellular Space
Female
Growth Hormone
Homeostasis
Human Growth Hormone
Humans
Insulin-Like Growth Factor I
Male
Middle Aged
Plasma Volume
Renin

Cite this

Long-term effects of growth hormone (GH) on body fluid distribution in GH deficient adults: a four months double blind placebo controlled trial. / Fisker, Sidse; Rosenfalck, A M; Frandsen, E et al.
In: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 140, No. 1, 01.1999, p. 11-6.

Research output: Contribution to journal › Journal article › Research › peer-review

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AU - Fisker, Sidse

AU - Rosenfalck, A M

AU - Frandsen, E

AU - Jørgensen, J O

AU - Hilsted, J

AU - Christiansen, J S

PY - 1999/1

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N2 - Short-term growth hormone (GH) treatment normalises body fluid distribution in adult GH deficient patients, but the impact of long-term treatment on body fluid homeostasis has hitherto not been thoroughly examined in placebo controlled trials. To investigate if the water retaining effect of GH persists for a longer time we examined the impact of 4 months GH treatment on extracellular volume (ECV) and plasma volume (PV) in GH deficient adults.

AB - Short-term growth hormone (GH) treatment normalises body fluid distribution in adult GH deficient patients, but the impact of long-term treatment on body fluid homeostasis has hitherto not been thoroughly examined in placebo controlled trials. To investigate if the water retaining effect of GH persists for a longer time we examined the impact of 4 months GH treatment on extracellular volume (ECV) and plasma volume (PV) in GH deficient adults.

KW - Adult

KW - Blood Pressure

KW - Body Composition

KW - Body Fluids

KW - Double-Blind Method

KW - Extracellular Space

KW - Female

KW - Growth Hormone

KW - Homeostasis

KW - Human Growth Hormone

KW - Humans

KW - Insulin-Like Growth Factor I

KW - Male

KW - Middle Aged

KW - Plasma Volume

KW - Renin

UR - https://www.scopus.com/pages/publications/0033011641

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SN - 0804-4643

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EP - 16

JO - European journal of endocrinology / European Federation of Endocrine Societies

JF - European journal of endocrinology / European Federation of Endocrine Societies

IS - 1

ER -

Long-term effects of growth hormone (GH) on body fluid distribution in GH deficient adults: a four months double blind placebo controlled trial

Abstract

Keywords

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