Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Lolland-Falster Health Study: Study protocol for a household-based prospective cohort study

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Response to Letter to the Editor: A misleading CFS prevalence estimate in DanFunD

    Research output: Contribution to journalComment/debateResearch

  2. Validity of the diagnosis of appendicitis in the Danish National Patient Register

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Number of hospital contacts with alcohol problems predicts later risk of alcoholic liver cirrhosis

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Two-fold risk of pneumonia and respiratory mortality in individuals with myeloproliferative neoplasm: A population-based cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Estimates of prediabetes and undiagnosed type 2 diabetes in Denmark: The end of an epidemic or a diagnostic artefact?

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Evidence of immune elimination, immuno-editing and immune escape in patients with hematological cancer

    Research output: Contribution to journalReviewResearchpeer-review

  4. Occupational lifting predicts hospital admission due to low back pain in a cohort of airport baggage handlers

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

INTRODUCTION: Lolland-Falster consists of two islands in the southern part of Denmark where income is lower and life expectancy is shorter than in the general Danish population. It is a mixed rural-provincial area with approximately 100,000 inhabitants. The Lolland-Falster Health Study was initiated to gain knowledge on the determinants of health in this disadvantaged area.

METHODS: The study is a household-based prospective cohort study including people of all ages. The entire household of randomly selected inhabitants is allocated either to an invited group or to an uninvited, non-contacted control group. The data collection encompasses questionnaires, physical examination and biological samples, i.e. blood and urine for same-day analysis and biobank storage, and saliva and faeces also for biobank storage. The civil registration number links collected data for each individual, family and household, with information in Danish registers. The data collection started in February 2016 and is estimated to end by 2019 after the enrolment of 20,000 people.

ANALYSIS: A number of in-depth sub-studies are planned. Emphasis will be given to analysis of intra- and inter-family variations in health determinants, genetics, lifestyle and health status. Ethics: Region Zealand's Ethical Committee on Health Research (SJ-421) and the Danish Data Protection Agency (REG-24-2015) approved the study.

TRIAL REGISTRATION: Clinicaltrials.gov (NCT02482896). Strength and limitations of this study: The strength of this study is that Lolland-Falster Health Study is a useful scientific resource for investigating cross-sectional difference and time trends within and between individuals, families and households. LOFUS adds diversity to the previously collected Danish population studies in urbanized areas. The limitation is that data collection is expensive.

CONCLUSIONS: LOFUS will contribute to the knowledge on health in disadvantaged, rural-provincial areas.

Original languageEnglish
Book seriesScandinavian Journal of Public Health. Supplement
Volume48
Issue number4
Pages (from-to)382-390
Number of pages9
ISSN1403-4956
DOIs
Publication statusPublished - Jun 2020

    Research areas

  • cohort analysis, Epidemiology, family health, genetics, households, public health

ID: 55397387