Local biochemical and morphological differences in human Achilles tendinopathy: a case control study

Jessica Pingel; Fredberg U; Qvortrup K; Larsen J O; Peter  Schjerling; Katja Maria Heinemeier; Michael Kjær; Henning Langberg Jørgensen

doi:10.1186/1471-2474-13-53

Local biochemical and morphological differences in human Achilles tendinopathy: a case control study

Jessica Pingel, Fredberg U, Qvortrup K, Larsen J O, Peter Schjerling, Katja Maria Heinemeier, Michael Kjær, Henning Langberg Jørgensen

Department of Orthopaedic Surgery

55 Citations (Scopus)

Abstract

The incidence of Achilles tendinopathy is high and underlying etiology as well as biochemical and morphological pathology associated with the disease is largely unknown. The aim of the present study was to describe biochemical and morphological differences in chronic Achilles tendinopathy. The expressions of growth factors, inflammatory mediators and tendon morphology were determined in both chronically diseased and healthy tendon parts.

Original language	English
Journal	B M C Musculoskeletal Disorders
Volume	13
Pages (from-to)	53
ISSN	1471-2474
DOIs	https://doi.org/10.1186/1471-2474-13-53
Publication status	Published - 2012

Keywords

Achilles Tendon
Biopsy
Case-Control Studies
Chi-Square Distribution
Chronic Disease
Collagenases
Denmark
Fibrillar Collagens
Gene Expression Regulation
Genetic Markers
Humans
Inflammation Mediators
Intercellular Signaling Peptides and Proteins
Microscopy, Electron, Transmission
Polymerase Chain Reaction
RNA, Messenger
Tendinopathy
Tissue Inhibitor of Metalloproteinases

Access to Document

10.1186/1471-2474-13-53

Cite this

@article{cc7b8484538d4984bb05658b69deb54c,

title = "Local biochemical and morphological differences in human Achilles tendinopathy: a case control study",

abstract = "The incidence of Achilles tendinopathy is high and underlying etiology as well as biochemical and morphological pathology associated with the disease is largely unknown. The aim of the present study was to describe biochemical and morphological differences in chronic Achilles tendinopathy. The expressions of growth factors, inflammatory mediators and tendon morphology were determined in both chronically diseased and healthy tendon parts.",

keywords = "Achilles Tendon, Biopsy, Case-Control Studies, Chi-Square Distribution, Chronic Disease, Collagenases, Denmark, Fibrillar Collagens, Gene Expression Regulation, Genetic Markers, Humans, Inflammation Mediators, Intercellular Signaling Peptides and Proteins, Microscopy, Electron, Transmission, Polymerase Chain Reaction, RNA, Messenger, Tendinopathy, Tissue Inhibitor of Metalloproteinases",

author = "Jessica Pingel and Fredberg U and Qvortrup K and \{J O\}, Larsen and Peter Schjerling and Heinemeier, \{Katja Maria\} and Michael Kj{\ae}r and J{\o}rgensen, \{Henning Langberg\}",

year = "2012",

doi = "10.1186/1471-2474-13-53",

language = "English",

volume = "13",

pages = "53",

journal = "B M C Musculoskeletal Disorders",

issn = "1471-2474",

publisher = "BioMed Central Ltd",

}

TY - JOUR

T1 - Local biochemical and morphological differences in human Achilles tendinopathy

T2 - a case control study

AU - Pingel, Jessica

AU - U, Fredberg

AU - K, Qvortrup

AU - J O, Larsen

AU - Schjerling, Peter

AU - Heinemeier, Katja Maria

AU - Kjær, Michael

AU - Jørgensen, Henning Langberg

PY - 2012

Y1 - 2012

N2 - The incidence of Achilles tendinopathy is high and underlying etiology as well as biochemical and morphological pathology associated with the disease is largely unknown. The aim of the present study was to describe biochemical and morphological differences in chronic Achilles tendinopathy. The expressions of growth factors, inflammatory mediators and tendon morphology were determined in both chronically diseased and healthy tendon parts.

AB - The incidence of Achilles tendinopathy is high and underlying etiology as well as biochemical and morphological pathology associated with the disease is largely unknown. The aim of the present study was to describe biochemical and morphological differences in chronic Achilles tendinopathy. The expressions of growth factors, inflammatory mediators and tendon morphology were determined in both chronically diseased and healthy tendon parts.

KW - Achilles Tendon

KW - Biopsy

KW - Case-Control Studies

KW - Chi-Square Distribution

KW - Chronic Disease

KW - Collagenases

KW - Denmark

KW - Fibrillar Collagens

KW - Gene Expression Regulation

KW - Genetic Markers

KW - Humans

KW - Inflammation Mediators

KW - Intercellular Signaling Peptides and Proteins

KW - Microscopy, Electron, Transmission

KW - Polymerase Chain Reaction

KW - RNA, Messenger

KW - Tendinopathy

KW - Tissue Inhibitor of Metalloproteinases

UR - https://www.scopus.com/pages/publications/84859361490

U2 - 10.1186/1471-2474-13-53

DO - 10.1186/1471-2474-13-53

M3 - Journal article

C2 - 22480275

SN - 1471-2474

VL - 13

SP - 53

JO - B M C Musculoskeletal Disorders

JF - B M C Musculoskeletal Disorders

ER -

Local biochemical and morphological differences in human Achilles tendinopathy: a case control study

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this