Leiomyoma of the ciliary body. Report of 2 cases

S Heegaard; P K Jensen; E Scherfig; J U Prause

doi:10.1034/j.1600-0420.1999.770622.x

Leiomyoma of the ciliary body. Report of 2 cases

S Heegaard, P K Jensen, E Scherfig, J U Prause

14 Citations (Scopus)

Abstract

PURPOSE AND METHODS: The files of the Eye Pathology Institute contain only two cases of leiomyoma of the ciliary body. The diagnoses were re-evaluated, applying modern immunostainings.

RESULTS: The tumors were composed of interlacing fascicles of spindle-shaped cells with bright eosinophilic cytoplasm and cigar-shaped nuclei. Both tumors were well-vascularized, mostly by thin, branching capillaries. Larger vessels were also seen. In one case the tumor perforated the sclera. The tumor cells reacted with the reticulum stain and the Masson trichrome and were positive for antibodies against: smooth muscle actin (SMA), muscle specific actin (MSA), laminin and vimentin (one case).

CONCLUSION: Leiomyoma of the ciliary body is a rare smooth muscle cell tumor that may arise from either pericytes, ciliary - or intrascleral heterotopic muscle.

Original language	English
Journal	Acta Ophthalmologica Scandinavica
Volume	77
Issue number	6
Pages (from-to)	709-12
Number of pages	4
ISSN	1395-3907
DOIs	https://doi.org/10.1034/j.1600-0420.1999.770622.x
Publication status	Published - Dec 1999
Externally published	Yes

Keywords

Actins/immunology
Adult
Antibodies, Neoplasm/analysis
Biomarkers, Tumor
Biopsy
Ciliary Body/diagnostic imaging
Diagnosis, Differential
Eye Enucleation
Female
Humans
Laminin/immunology
Leiomyoma/diagnostic imaging
Male
Ultrasonography
Uveal Neoplasms/diagnostic imaging
Vimentin/immunology

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10.1034/j.1600-0420.1999.770622.x

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title = "Leiomyoma of the ciliary body. Report of 2 cases",

abstract = "PURPOSE AND METHODS: The files of the Eye Pathology Institute contain only two cases of leiomyoma of the ciliary body. The diagnoses were re-evaluated, applying modern immunostainings.RESULTS: The tumors were composed of interlacing fascicles of spindle-shaped cells with bright eosinophilic cytoplasm and cigar-shaped nuclei. Both tumors were well-vascularized, mostly by thin, branching capillaries. Larger vessels were also seen. In one case the tumor perforated the sclera. The tumor cells reacted with the reticulum stain and the Masson trichrome and were positive for antibodies against: smooth muscle actin (SMA), muscle specific actin (MSA), laminin and vimentin (one case).CONCLUSION: Leiomyoma of the ciliary body is a rare smooth muscle cell tumor that may arise from either pericytes, ciliary - or intrascleral heterotopic muscle.",

keywords = "Actins/immunology, Adult, Antibodies, Neoplasm/analysis, Biomarkers, Tumor, Biopsy, Ciliary Body/diagnostic imaging, Diagnosis, Differential, Eye Enucleation, Female, Humans, Laminin/immunology, Leiomyoma/diagnostic imaging, Male, Ultrasonography, Uveal Neoplasms/diagnostic imaging, Vimentin/immunology",

author = "S Heegaard and Jensen, \{P K\} and E Scherfig and Prause, \{J U\}",

year = "1999",

month = dec,

doi = "10.1034/j.1600-0420.1999.770622.x",

language = "English",

volume = "77",

pages = "709--12",

journal = "Acta Ophthalmologica Scandinavica",

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TY - JOUR

T1 - Leiomyoma of the ciliary body. Report of 2 cases

AU - Heegaard, S

AU - Jensen, P K

AU - Scherfig, E

AU - Prause, J U

PY - 1999/12

Y1 - 1999/12

N2 - PURPOSE AND METHODS: The files of the Eye Pathology Institute contain only two cases of leiomyoma of the ciliary body. The diagnoses were re-evaluated, applying modern immunostainings.RESULTS: The tumors were composed of interlacing fascicles of spindle-shaped cells with bright eosinophilic cytoplasm and cigar-shaped nuclei. Both tumors were well-vascularized, mostly by thin, branching capillaries. Larger vessels were also seen. In one case the tumor perforated the sclera. The tumor cells reacted with the reticulum stain and the Masson trichrome and were positive for antibodies against: smooth muscle actin (SMA), muscle specific actin (MSA), laminin and vimentin (one case).CONCLUSION: Leiomyoma of the ciliary body is a rare smooth muscle cell tumor that may arise from either pericytes, ciliary - or intrascleral heterotopic muscle.

AB - PURPOSE AND METHODS: The files of the Eye Pathology Institute contain only two cases of leiomyoma of the ciliary body. The diagnoses were re-evaluated, applying modern immunostainings.RESULTS: The tumors were composed of interlacing fascicles of spindle-shaped cells with bright eosinophilic cytoplasm and cigar-shaped nuclei. Both tumors were well-vascularized, mostly by thin, branching capillaries. Larger vessels were also seen. In one case the tumor perforated the sclera. The tumor cells reacted with the reticulum stain and the Masson trichrome and were positive for antibodies against: smooth muscle actin (SMA), muscle specific actin (MSA), laminin and vimentin (one case).CONCLUSION: Leiomyoma of the ciliary body is a rare smooth muscle cell tumor that may arise from either pericytes, ciliary - or intrascleral heterotopic muscle.

KW - Actins/immunology

KW - Adult

KW - Antibodies, Neoplasm/analysis

KW - Biomarkers, Tumor

KW - Biopsy

KW - Ciliary Body/diagnostic imaging

KW - Diagnosis, Differential

KW - Eye Enucleation

KW - Female

KW - Humans

KW - Laminin/immunology

KW - Leiomyoma/diagnostic imaging

KW - Male

KW - Ultrasonography

KW - Uveal Neoplasms/diagnostic imaging

KW - Vimentin/immunology

UR - https://www.scopus.com/pages/publications/0033430963

U2 - 10.1034/j.1600-0420.1999.770622.x

DO - 10.1034/j.1600-0420.1999.770622.x

M3 - Journal article

C2 - 10634570

SN - 1395-3907

VL - 77

SP - 709

EP - 712

JO - Acta Ophthalmologica Scandinavica

JF - Acta Ophthalmologica Scandinavica

IS - 6

ER -

Leiomyoma of the ciliary body. Report of 2 cases

Abstract

Keywords

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