Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Leg oxygen uptake in the initial phase of intense exercise is slowed by a marked reduction in oxygen delivery

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Variable reliability of surrogate measures of insulin sensitivity after Roux-en-Y gastric bypass

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. In vivo and in vitro degradation of peptide YY3-36 to inactive peptide YY3-34 in humans

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Mapping the calcitonin receptor in human brain stem

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Delayed growth, motor function and learning in preterm pigs during early postnatal life

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Body height and arterial pressure in seated and supine young males during +2 G centrifugation

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations
The present study examined whether a marked reduction in oxygen delivery, unlike findings in moderate-intensity exercise, would slow leg oxygen uptake (Vo2) kinetics during intense exercise (86 ± 3% of incremental test peak power). Seven healthy males (26 ± 1 years, means ± SE) performed one-legged knee-extensor exercise (60 ± 3 W) for 4 min in a control setting (CON) and with arterial infusion of N(G)-monomethyl-l-arginine and indomethacin in the working leg to reduce blood flow by inhibiting formation of nitric oxide and prostanoids (double blockade; DB). In DB leg blood flow (LBF) and oxygen delivery during the first minute of exercise were 25-50% lower (P
Original languageEnglish
JournalA J P: Regulatory, Integrative and Comparative Physiology (Online)
Volume305
Issue number3
Pages (from-to)R313-21
ISSN1522-1490
DOIs
Publication statusPublished - 1 Aug 2013

    Research areas

  • Adult, Blood Gas Analysis, Blood Pressure, Cyclooxygenase Inhibitors, Data Interpretation, Statistical, Enzyme Inhibitors, Exercise, Hemodynamics, Humans, Hydrogen-Ion Concentration, Indomethacin, Lactic Acid, Leg, Male, Muscle Fibers, Fast-Twitch, Muscle, Skeletal, Oxygen Consumption, Potassium, Recruitment, Neurophysiological, Regional Blood Flow, omega-N-Methylarginine

ID: 41954214