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Knee Extension Strength Measures Indicating Probable Sarcopenia Is Associated with Health-Related Outcomes and a Strong Predictor of 1-Year Mortality in Patients Following Hip Fracture Surgery

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To examine if knee-extension strength (KES) measures indicating probable sarcopenia are associated with health-related outcomes and if KES and hand grip strength (HGS) measures are associated with 1-year mortality after hip fracture. Two groups of older patients with hip fracture had either HGS (n = 32) or KES (n = 150) assessed during their acute hospital stay. Cut-points for HGS (<27 kg for men and <16 kg for women), and cut-points for maximal isometric KES (non-fractured limb), being the lowest sex-specific quintile (<23.64 kg for men and <15.24 kg for women), were used to examine association with health-related outcomes and 1-year mortality. Overall, 1-year mortality was 12.6% in the two strength groups, of which 47% (HGS) and 46% (KES) respectively, were classified as probable sarcopenia. Probable sarcopenia patients (KES) had lower prefracture function, performed poorly in mobility measures and expressed a greater concern of falling compared to their stronger counterparts. Hazard ratio for 1-year mortality was 2.7 (95%CI = 0.49-14.7, p = 0.3) for HGS and 9.8 (95%CI = 2.2-43.0, p = 0.002) for KES for probable sarcopenia patients compared to those not. Sex-specific KES measures indicating sarcopenia is associated with health-related outcomes and a strong predictor of 1-year mortality after hip fracture.

Original languageEnglish
Article number8
JournalGeriatrics (Basel, Switzerland)
Issue number1
Pages (from-to)1-13
Number of pages13
Publication statusPublished - 15 Jan 2021

Bibliographical note

Publisher Copyright:
© 2021 by the authors.

Copyright 2021 Elsevier B.V., All rights reserved.

    Research areas

  • Fear of falling, Health-related outcomes, Hip fractures, Mortality, Muscle strength, Sarcopenia, muscle strength, fear of falling, hip fractures, health-related outcomes, mortality, sarcopenia

ID: 61845327