Kateterbaseret behandling til patienter med akut lungeemboli

Emilie Sonne-Holm; Lia E Bang; Jørn Carlsen; Asger Andersen; Mikkel Hougaard; Martin Kirk Christensen; Lene Holmvang; Rikke Sørensen; Mads Ersbøll; Jesper Kjærgaard

doi:10.61409/V07250571

Kateterbaseret behandling til patienter med akut lungeemboli

Translated title of the contribution: Catheter-based treatment for patients with acute pulmonary embolism

Emilie Sonne-Holm^*, Lia E Bang, Jørn Carlsen, Asger Andersen, Mikkel Hougaard, Martin Kirk Christensen, Lene Holmvang, Rikke Sørensen, Mads Ersbøll, Jesper Kjærgaard

^*Corresponding author for this work

Department of Cardiology

Abstract

Catheter-based therapies such as catheter-direceted thrombolysis, ultrasound-assisted thrombolysis, and mechanical embolectomy are emerging as alternatives for intermediate-high risk pulmonary embolism, offering targeted treatment with reduced bleeding risk. Early studies show promising outcomes but evidence remains limited. Ongoing randomized trials, including HI-PEITHO and PEERLESS II, aim to clarify efficacy and safety. Until results are available, treatment should be guided by individual risk assessment, local expertise, and centre capabilities, as argued in this review.

Translated title of the contribution	Catheter-based treatment for patients with acute pulmonary embolism
Original language	Danish
Article number	V07250571
Journal	Ugeskrift for Laeger
Volume	187
Issue number	51
Pages (from-to)	1-8
Number of pages	8
ISSN	0041-5782
DOIs	https://doi.org/10.61409/V07250571
Publication status	Published - 15 Dec 2025

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10.61409/V07250571Licence: CC BY-NC-ND

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title = "Kateterbaseret behandling til patienter med akut lungeemboli",

abstract = "Catheter-based therapies such as catheter-direceted thrombolysis, ultrasound-assisted thrombolysis, and mechanical embolectomy are emerging as alternatives for intermediate-high risk pulmonary embolism, offering targeted treatment with reduced bleeding risk. Early studies show promising outcomes but evidence remains limited. Ongoing randomized trials, including HI-PEITHO and PEERLESS II, aim to clarify efficacy and safety. Until results are available, treatment should be guided by individual risk assessment, local expertise, and centre capabilities, as argued in this review.",

keywords = "Humans, Pulmonary Embolism/therapy, Thrombolytic Therapy/methods, Acute Disease, Embolectomy/methods, Fibrinolytic Agents/administration \& dosage, Treatment Outcome, Catheterization/methods, Mechanical Thrombolysis/methods",

author = "Emilie Sonne-Holm and Bang, \{Lia E\} and J{\o}rn Carlsen and Asger Andersen and Mikkel Hougaard and Christensen, \{Martin Kirk\} and Lene Holmvang and Rikke S{\o}rensen and Mads Ersb{\o}ll and Jesper Kj{\ae}rgaard",

note = "Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.",

year = "2025",

month = dec,

day = "15",

doi = "10.61409/V07250571",

language = "Dansk",

volume = "187",

pages = "1--8",

journal = "Ugeskrift for Laeger",

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TY - JOUR

T1 - Kateterbaseret behandling til patienter med akut lungeemboli

AU - Sonne-Holm, Emilie

AU - Bang, Lia E

AU - Carlsen, Jørn

AU - Andersen, Asger

AU - Hougaard, Mikkel

AU - Christensen, Martin Kirk

AU - Holmvang, Lene

AU - Sørensen, Rikke

AU - Ersbøll, Mads

AU - Kjærgaard, Jesper

N1 - Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

PY - 2025/12/15

Y1 - 2025/12/15

N2 - Catheter-based therapies such as catheter-direceted thrombolysis, ultrasound-assisted thrombolysis, and mechanical embolectomy are emerging as alternatives for intermediate-high risk pulmonary embolism, offering targeted treatment with reduced bleeding risk. Early studies show promising outcomes but evidence remains limited. Ongoing randomized trials, including HI-PEITHO and PEERLESS II, aim to clarify efficacy and safety. Until results are available, treatment should be guided by individual risk assessment, local expertise, and centre capabilities, as argued in this review.

AB - Catheter-based therapies such as catheter-direceted thrombolysis, ultrasound-assisted thrombolysis, and mechanical embolectomy are emerging as alternatives for intermediate-high risk pulmonary embolism, offering targeted treatment with reduced bleeding risk. Early studies show promising outcomes but evidence remains limited. Ongoing randomized trials, including HI-PEITHO and PEERLESS II, aim to clarify efficacy and safety. Until results are available, treatment should be guided by individual risk assessment, local expertise, and centre capabilities, as argued in this review.

KW - Humans

KW - Pulmonary Embolism/therapy

KW - Thrombolytic Therapy/methods

KW - Acute Disease

KW - Embolectomy/methods

KW - Fibrinolytic Agents/administration & dosage

KW - Treatment Outcome

KW - Catheterization/methods

KW - Mechanical Thrombolysis/methods

UR - https://www.scopus.com/pages/publications/105026639359

U2 - 10.61409/V07250571

DO - 10.61409/V07250571

M3 - Review

C2 - 41489142

SN - 0041-5782

VL - 187

SP - 1

EP - 8

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 51

M1 - V07250571

ER -

Kateterbaseret behandling til patienter med akut lungeemboli

Abstract

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