Kardiovaskulære risici ved behandling med nonsteroide antiinflammatoriske lægemidler

Morten Schmidt; Emil Loldrup Fosbøl; Christian Torp-Pedersen; Anne-Marie Schjerning Olsen; bo Christensen; Gunnar H Gislason

Kardiovaskulære risici ved behandling med nonsteroide antiinflammatoriske lægemidler

Translated title of the contribution: Cardiovascular risks of non-steroidal anti-inflammatory drugs treatment

Morten Schmidt, Emil Loldrup Fosbøl, Christian Torp-Pedersen, Anne-Marie Schjerning Olsen, bo Christensen, Gunnar H Gislason

Department of Cardiology

Abstract

Non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely used drugs. Current evidence supports that all NSAIDs increase the risk of heart failure and elevate blood pressure, whereas the risk of thrombotic events varies with the type of drug. Use of newer selective cyclooxygenase-2 inhibitors has been associated with a substantial vascular risk but increasing concern also relates to traditional NSAIDs, in particular diclofenac. This review summarizes the current evidence regarding the cardiovascular safety of NSAIDs and presents recommendations for their use.

Translated title of the contribution	Cardiovascular risks of non-steroidal anti-inflammatory drugs treatment
Original language	Danish
Article number	V08160612
Journal	Ugerskrift for Læger
Volume	178
Issue number	52
Pages (from-to)	V08160612
ISSN	1603-6824
Publication status	Published - 26 Dec 2016

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http://ugeskriftet.dk/videnskab/kardiovaskulaere-risici-ved-behandling-med-nonsteroide-antiinflammatoriske-laegemidler

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Schmidt, M., Fosbøl, E. L., Torp-Pedersen, C., Schjerning Olsen, A.-M., Christensen, B., & Gislason, G. H. (2016). Kardiovaskulære risici ved behandling med nonsteroide antiinflammatoriske lægemidler. Ugerskrift for Læger, 178(52), V08160612. Article V08160612. http://ugeskriftet.dk/videnskab/kardiovaskulaere-risici-ved-behandling-med-nonsteroide-antiinflammatoriske-laegemidler

Schmidt, M, Fosbøl, EL , Torp-Pedersen, C , Schjerning Olsen, A-M, Christensen, B & Gislason, GH 2016, 'Kardiovaskulære risici ved behandling med nonsteroide antiinflammatoriske lægemidler', Ugerskrift for Læger, vol. 178, no. 52, V08160612, pp. V08160612. <http://ugeskriftet.dk/videnskab/kardiovaskulaere-risici-ved-behandling-med-nonsteroide-antiinflammatoriske-laegemidler>

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abstract = "Non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely used drugs. Current evidence supports that all NSAIDs increase the risk of heart failure and elevate blood pressure, whereas the risk of thrombotic events varies with the type of drug. Use of newer selective cyclooxygenase-2 inhibitors has been associated with a substantial vascular risk but increasing concern also relates to traditional NSAIDs, in particular diclofenac. This review summarizes the current evidence regarding the cardiovascular safety of NSAIDs and presents recommendations for their use.",

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AU - Schjerning Olsen, Anne-Marie

AU - Christensen, bo

AU - Gislason, Gunnar H

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AB - Non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely used drugs. Current evidence supports that all NSAIDs increase the risk of heart failure and elevate blood pressure, whereas the risk of thrombotic events varies with the type of drug. Use of newer selective cyclooxygenase-2 inhibitors has been associated with a substantial vascular risk but increasing concern also relates to traditional NSAIDs, in particular diclofenac. This review summarizes the current evidence regarding the cardiovascular safety of NSAIDs and presents recommendations for their use.

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Kardiovaskulære risici ved behandling med nonsteroide antiinflammatoriske lægemidler

Abstract

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