Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Ischemic heart failure as a complication of incident acute myocardial infarction: Timing and time trends: A national analysis including 78,814 Danish patients during 2000-2009

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

APA

CBE

MLA

Vancouver

Author

Bibtex

@article{3ad9f791dfae412598a21821fd0e5537,
title = "Ischemic heart failure as a complication of incident acute myocardial infarction: Timing and time trends: A national analysis including 78,814 Danish patients during 2000-2009",
abstract = "AIM: Heart failure is a serious complication of acute myocardial infarction leading to poor prognosis. We aimed at exploring time trends of heart failure and their impact on mortality among patients with an incident acute myocardial infarction.METHODS: From the National Patient Danish Registry we collected data on all patients hospitalized with an incident of acute myocardial infarction during 2000-2009 and identified cases with in-hospital heart failure (presented on admission or developing heart failure during acute myocardial infarction hospitalization) or post-discharge heart failure (a hospitalization or outpatient visit following acute myocardial infarction discharge), and assessed in-hospital, 30-day and 1-year mortality.RESULTS: Of the 78,814 patients included in the study, 10,248 (13.0{\%}) developed in-hospital heart failure. The odds of in-hospital heart failure declined 0.9{\%} per year (odds ratio=0.991, 95{\%} confidence interval: 0.983-0.999). In-hospital heart failure was associated with 13{\%} (odds ratio=1.13, 95{\%} confidence interval: 1.06-1.20) and 14{\%} (odds ratio=1.14, 95{\%} confidence interval: 1.07-1.20) higher in-hospital and 30-day mortality, respectively. Of the 61,637 patients discharged alive without in-hospital heart failure, 5978 (9.7{\%}) experienced post-discharge heart failure, 4116 (6.7{\%}) were hospitalized and 1862 (3.0{\%}) were diagnosed at outpatient clinics. The risk of heart failure requiring hospitalization declined 5.5{\%} per year (hazard ratio=0.945, 95{\%} confidence interval: 0.934-0.955) whereas the risk of heart failure diagnosed at outpatient clinics increased 13.4{\%} per year (hazard ratio=1.134, 95{\%} confidence interval: 1.115-1.153). Post-discharge heart failure was associated with 239{\%} (hazard ratio=3.39, 95{\%} confidence interval: 3.18-3.63) higher 1-year mortality.CONCLUSIONS: In-hospital and post-discharge heart failure requiring hospitalization decreased whereas post-discharge heart failure diagnosed at outpatient clinics increased among incident acute myocardial infarction patients during 2000-2009. The development of heart failure, especially after acute myocardial infarction discharge, indicates a poor prognosis.",
keywords = "Adult, Aged, Aged, 80 and over, Denmark/epidemiology, Female, Heart Failure/epidemiology, Hospitalization/statistics & numerical data, Humans, Male, Middle Aged, Myocardial Infarction/complications, Prognosis, Registries, Risk Factors, Time Factors",
author = "Gerhard Sulo and Enxhela Sulo and Torben J{\o}rgensen and Allan Linneberg and Eva Prescott and Tell, {Grethe S} and Merete Osler",
year = "2020",
month = "5",
doi = "10.1177/1403494819829333",
language = "English",
volume = "48",
pages = "294--302",
journal = "Scandinavian Journal of Public Health. Supplement",
issn = "1403-4956",
publisher = "Sage Publications Ltd",
number = "3",

}

RIS

TY - JOUR

T1 - Ischemic heart failure as a complication of incident acute myocardial infarction

T2 - Timing and time trends: A national analysis including 78,814 Danish patients during 2000-2009

AU - Sulo, Gerhard

AU - Sulo, Enxhela

AU - Jørgensen, Torben

AU - Linneberg, Allan

AU - Prescott, Eva

AU - Tell, Grethe S

AU - Osler, Merete

PY - 2020/5

Y1 - 2020/5

N2 - AIM: Heart failure is a serious complication of acute myocardial infarction leading to poor prognosis. We aimed at exploring time trends of heart failure and their impact on mortality among patients with an incident acute myocardial infarction.METHODS: From the National Patient Danish Registry we collected data on all patients hospitalized with an incident of acute myocardial infarction during 2000-2009 and identified cases with in-hospital heart failure (presented on admission or developing heart failure during acute myocardial infarction hospitalization) or post-discharge heart failure (a hospitalization or outpatient visit following acute myocardial infarction discharge), and assessed in-hospital, 30-day and 1-year mortality.RESULTS: Of the 78,814 patients included in the study, 10,248 (13.0%) developed in-hospital heart failure. The odds of in-hospital heart failure declined 0.9% per year (odds ratio=0.991, 95% confidence interval: 0.983-0.999). In-hospital heart failure was associated with 13% (odds ratio=1.13, 95% confidence interval: 1.06-1.20) and 14% (odds ratio=1.14, 95% confidence interval: 1.07-1.20) higher in-hospital and 30-day mortality, respectively. Of the 61,637 patients discharged alive without in-hospital heart failure, 5978 (9.7%) experienced post-discharge heart failure, 4116 (6.7%) were hospitalized and 1862 (3.0%) were diagnosed at outpatient clinics. The risk of heart failure requiring hospitalization declined 5.5% per year (hazard ratio=0.945, 95% confidence interval: 0.934-0.955) whereas the risk of heart failure diagnosed at outpatient clinics increased 13.4% per year (hazard ratio=1.134, 95% confidence interval: 1.115-1.153). Post-discharge heart failure was associated with 239% (hazard ratio=3.39, 95% confidence interval: 3.18-3.63) higher 1-year mortality.CONCLUSIONS: In-hospital and post-discharge heart failure requiring hospitalization decreased whereas post-discharge heart failure diagnosed at outpatient clinics increased among incident acute myocardial infarction patients during 2000-2009. The development of heart failure, especially after acute myocardial infarction discharge, indicates a poor prognosis.

AB - AIM: Heart failure is a serious complication of acute myocardial infarction leading to poor prognosis. We aimed at exploring time trends of heart failure and their impact on mortality among patients with an incident acute myocardial infarction.METHODS: From the National Patient Danish Registry we collected data on all patients hospitalized with an incident of acute myocardial infarction during 2000-2009 and identified cases with in-hospital heart failure (presented on admission or developing heart failure during acute myocardial infarction hospitalization) or post-discharge heart failure (a hospitalization or outpatient visit following acute myocardial infarction discharge), and assessed in-hospital, 30-day and 1-year mortality.RESULTS: Of the 78,814 patients included in the study, 10,248 (13.0%) developed in-hospital heart failure. The odds of in-hospital heart failure declined 0.9% per year (odds ratio=0.991, 95% confidence interval: 0.983-0.999). In-hospital heart failure was associated with 13% (odds ratio=1.13, 95% confidence interval: 1.06-1.20) and 14% (odds ratio=1.14, 95% confidence interval: 1.07-1.20) higher in-hospital and 30-day mortality, respectively. Of the 61,637 patients discharged alive without in-hospital heart failure, 5978 (9.7%) experienced post-discharge heart failure, 4116 (6.7%) were hospitalized and 1862 (3.0%) were diagnosed at outpatient clinics. The risk of heart failure requiring hospitalization declined 5.5% per year (hazard ratio=0.945, 95% confidence interval: 0.934-0.955) whereas the risk of heart failure diagnosed at outpatient clinics increased 13.4% per year (hazard ratio=1.134, 95% confidence interval: 1.115-1.153). Post-discharge heart failure was associated with 239% (hazard ratio=3.39, 95% confidence interval: 3.18-3.63) higher 1-year mortality.CONCLUSIONS: In-hospital and post-discharge heart failure requiring hospitalization decreased whereas post-discharge heart failure diagnosed at outpatient clinics increased among incident acute myocardial infarction patients during 2000-2009. The development of heart failure, especially after acute myocardial infarction discharge, indicates a poor prognosis.

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Denmark/epidemiology

KW - Female

KW - Heart Failure/epidemiology

KW - Hospitalization/statistics & numerical data

KW - Humans

KW - Male

KW - Middle Aged

KW - Myocardial Infarction/complications

KW - Prognosis

KW - Registries

KW - Risk Factors

KW - Time Factors

UR - http://www.scopus.com/inward/record.url?scp=85062463119&partnerID=8YFLogxK

U2 - 10.1177/1403494819829333

DO - 10.1177/1403494819829333

M3 - Journal article

VL - 48

SP - 294

EP - 302

JO - Scandinavian Journal of Public Health. Supplement

JF - Scandinavian Journal of Public Health. Supplement

SN - 1403-4956

IS - 3

ER -

ID: 56741276