Inverse relation between vitamin D and serum total immunoglobulin G in the Scandinavian Cystic Fibrosis Nutritional Study

T Pincikova; Kristine Kahr Nilsson; I E Moen; F Karpati; G Fluge; A Hollsing; Pernille Knudsen; A Lindblad; L Mared; T Pressler; L Hjelte; Scandinavian Cystic Fibrosis Study Consortium

doi:10.1038/ejcn.2010.194

Inverse relation between vitamin D and serum total immunoglobulin G in the Scandinavian Cystic Fibrosis Nutritional Study

T Pincikova, Kristine Kahr Nilsson, I E Moen, F Karpati, G Fluge, A Hollsing, Pernille Knudsen, A Lindblad, L Mared, T Pressler, L Hjelte, Scandinavian Cystic Fibrosis Study Consortium

Department of Paediatrics and Adolescent Medicine

55 Citations (Scopus)

Abstract

The hallmark of cystic fibrosis (CF) is chronic lung inflammation. The severity of lung disease is closely correlated with immunoglobulin G (IgG) levels. Beyond its contribution to the bone health, the importance of vitamin D has not been fully recognized owing to the lack of human studies providing evidence of its benefit. In the context of the recently described immunomodulatory functions of vitamin D, we aimed to assess the relationship between vitamin D and IgG levels.

Original language	English
Journal	European Journal of Clinical Nutrition
Volume	65
Issue number	1
Pages (from-to)	102-9
Number of pages	8
ISSN	0954-3007
DOIs	https://doi.org/10.1038/ejcn.2010.194
Publication status	Published - 2011

Keywords

Adolescent
Adult
Aged
Child
Child, Preschool
Cross-Sectional Studies
Cystic Fibrosis
Denmark
Dietary Supplements
Ergocalciferols
Female
Humans
Immunoglobulin G
Infant
Male
Middle Aged
Norway
Nutritional Status
Regression Analysis
Sweden
Vitamin D
Young Adult

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10.1038/ejcn.2010.194

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Pincikova, T., Nilsson, K. K., Moen, I. E., Karpati, F., Fluge, G., Hollsing, A., Knudsen, P., Lindblad, A., Mared, L., Pressler, T., Hjelte, L., & Scandinavian Cystic Fibrosis Study Consortium (2011). Inverse relation between vitamin D and serum total immunoglobulin G in the Scandinavian Cystic Fibrosis Nutritional Study. European Journal of Clinical Nutrition, 65(1), 102-9. https://doi.org/10.1038/ejcn.2010.194

Pincikova, T, Nilsson, KK, Moen, IE, Karpati, F, Fluge, G, Hollsing, A, Knudsen, P, Lindblad, A, Mared, L, Pressler, T, Hjelte, L & Scandinavian Cystic Fibrosis Study Consortium 2011, 'Inverse relation between vitamin D and serum total immunoglobulin G in the Scandinavian Cystic Fibrosis Nutritional Study', European Journal of Clinical Nutrition, vol. 65, no. 1, pp. 102-9. https://doi.org/10.1038/ejcn.2010.194

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abstract = "The hallmark of cystic fibrosis (CF) is chronic lung inflammation. The severity of lung disease is closely correlated with immunoglobulin G (IgG) levels. Beyond its contribution to the bone health, the importance of vitamin D has not been fully recognized owing to the lack of human studies providing evidence of its benefit. In the context of the recently described immunomodulatory functions of vitamin D, we aimed to assess the relationship between vitamin D and IgG levels.",

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AU - Pincikova, T

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AU - Moen, I E

AU - Karpati, F

AU - Fluge, G

AU - Hollsing, A

AU - Knudsen, Pernille

AU - Lindblad, A

AU - Mared, L

AU - Pressler, T

AU - Hjelte, L

AU - Scandinavian Cystic Fibrosis Study Consortium

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AB - The hallmark of cystic fibrosis (CF) is chronic lung inflammation. The severity of lung disease is closely correlated with immunoglobulin G (IgG) levels. Beyond its contribution to the bone health, the importance of vitamin D has not been fully recognized owing to the lack of human studies providing evidence of its benefit. In the context of the recently described immunomodulatory functions of vitamin D, we aimed to assess the relationship between vitamin D and IgG levels.

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KW - Aged

KW - Child

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KW - Cross-Sectional Studies

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KW - Denmark

KW - Dietary Supplements

KW - Ergocalciferols

KW - Female

KW - Humans

KW - Immunoglobulin G

KW - Infant

KW - Male

KW - Middle Aged

KW - Norway

KW - Nutritional Status

KW - Regression Analysis

KW - Sweden

KW - Vitamin D

KW - Young Adult

U2 - 10.1038/ejcn.2010.194

DO - 10.1038/ejcn.2010.194

M3 - Journal article

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SN - 0954-3007

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JO - European Journal of Clinical Nutrition

JF - European Journal of Clinical Nutrition

IS - 1

ER -

Inverse relation between vitamin D and serum total immunoglobulin G in the Scandinavian Cystic Fibrosis Nutritional Study

Abstract

Keywords

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