Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Intravascular assessment of coronary arteries in patients with cyanotic congenital heart disease

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. The role of the Heart Team in the planning of aortic valve replacement

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Will the Evolut Low Risk trial change my practice?

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Durability of transcatheter bioprosthetic aortic valves: the story so far

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. The EuroIntervention health check 2019

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Interaction of ischaemic postconditioning and thrombectomy in patients with ST-elevation myocardial infarction

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Outcome after heart-lung or lung transplantation in patients with Eisenmenger syndrome

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Transcatheter Aortic Valve Replacement: Role of Multimodality Imaging in Common and Complex Clinical Scenarios

    Research output: Contribution to journalReviewResearchpeer-review

  4. Coronary CT Angiography in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Simplification of Transcatheter Aortic Valve Replacement

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

AIMS: Patients with cyanotic congenital heart disease (CCHD) have been suggested to develop less atherosclerosis than the general population. This study aimed to evaluate the extent of coronary atherosclerosis in patients with CCHD using intravascular ultrasound (IVUS) and near-infrared spectroscopy (NIRS).

METHODS AND RESULTS: Fifteen patients with CCHD (women, 9; median age, 53 years) and 14 acyanotic controls (women, 6; median age, 53 years) were examined with IVUS-NIRS of the right coronary artery (RCA). The patients with CCHD presented with a larger RCA diameter than the controls (external-elastic-membrane diameter, 6.1 [4.8-6.7] vs. 4.7 [4.1-5.1] mm, respectively; p=0.01). No difference in area-stenosis was found between the patients and the controls (15.8% [12.3-19.7%] vs. 15.2% [9.5-18.8%]; p=0.87). The presence of lipid by NIRS was noted in 43% of patients with CCHD and in 92% of the controls; however, no differences in total or max-4-mm lipid-core-burden-index (LCBI) or in plasma lipid-profile were found.

CONCLUSIONS: Patients with CCHD presented with larger coronary arteries than acyanotic controls. No difference in the degree of area-stenosis in the coronary arteries was found between the cyanotic and acyanotic patients; however, a lower proportion of patients with CCHD showed a positive LCBI.

Original languageEnglish
JournalEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Volume14
Issue number17
Pages (from-to)1744-1750
ISSN1774-024X
DOIs
Publication statusPublished - 20 Apr 2019

    Research areas

  • Coronary Artery Disease, Coronary Vessels, Cyanosis, Female, Humans, Male, Middle Aged, Plaque, Atherosclerotic, Ultrasonography, Interventional

ID: 56429639