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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat

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More than half of pregnant women in the Western world report intake of mild analgesics, and some of these drugs have been associated with anti-androgenic effects in animal experiments. Intrauterine exposure to anti-androgens is suspected to contribute to the recent increase in male reproductive problems, and many of the anti-androgenic compounds are like the mild analgesics potent inhibitors of prostaglandin synthesis. Therefore, it appears imperative to further investigate the potential endocrine disrupting properties of mild analgesics.
Original languageEnglish
JournalHuman Reproduction
Volume26
Issue number1
Pages (from-to)235-44
Number of pages10
ISSN0268-1161
DOIs
Publication statusPublished - 1 Jan 2011

ID: 31058620