Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Intraoperative flow profiles of arterial and venous bypass grafts to the left coronary territory

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. 2019 EACTS Expert Consensus on long-term mechanical circulatory support

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Burden and causes for hospitalizations following coronary artery bypass grafting: a nationwide cohort study†

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Lung transplantation after ex vivo lung perfusion in two Scandinavian centres

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Indtag af chokolade versus slik i en medicinsk akutmodtagelse

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Myocardial infarction with simultaneous anterior and inferior ST-segment elevation

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Sportsdykning udfordrer både kredsløb og respiration

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

OBJECTIVES: The different mechanical and vasodilatory properties of arteries and veins may influence their flow profiles when used for coronary artery bypass grafting (CABG). This may be of significance when assessing the cut-off values for adequate flow. However, conduit-related flow differences are less examined.

METHODS: In a study of 268 patients, transit time flowmetry parameters of 336 arterial and 170 venous conduits all grafted to the left coronary territory were compared. With transit time flowmetry, the mean graft flow (MGF), pulsatility index, percentage of diastolic filling and percentage of backwards flow were measured. Conduit-related differences were further compared according to on- or off-pump CABG (ONCABG versus OPCABG) surgery.

RESULTS: Overall MGF and pulsatility index were comparable between arterial and venous grafts, but in arterial grafts, MGF was higher during ONCABG than during OPCABG (49.1 ± 35.3 ml/min vs 38.8 ± 26.6 ml/min; P = 0.003). Percentage of diastolic filling was higher in arterial grafts than in venous grafts (overall 71.0 ± 7.9% vs 63.7 ± 11.1%; ONCABG 69.9 ± 7.1% vs 63.9 ± 10.4%; OPCABG 71.9 ± 8.3% vs 63.4 ± 12.2%; all P < 0.001). Furthermore, percentage of backwards flow was higher in arterial grafts than in venous grafts in the overall (2.3 ± 3.2% vs 1.7 ± 3.2%, P = 0.002) and in the ONCABG (2.3 ± 3.2% vs 1.3 ± 2.5%, P < 0.001) cohorts. In venous grafts, percentage of backwards flow was lower during ONCABG versus OPCABG (1.3 ± 2.5% vs 2.6 ± 3.9%, P = 0.016).

CONCLUSIONS: No statistically significant difference was observed for MGF and pulsatility index between arterial and venous conduits. However, arterial grafts have significantly higher diastolic filling and backwards flow than venous grafts. Furthermore, arterial grafts have a significantly higher MGF in ONCABG versus OPCABG.

Original languageEnglish
JournalEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
Volume56
Issue number1
Pages (from-to)64-71
Number of pages8
ISSN1010-7940
DOIs
Publication statusPublished - 1 Jul 2019

ID: 58088776