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Intra-articular sodium hyaluronate 2 mL versus physiological saline 20 mL versus physiological saline 2 mL for painful knee osteoarthritis: a randomized clinical trial

C Lundsgaard, N Dufour, E Fallentin, P Winkel, C Gluud

60 Citations (Scopus)

Abstract

Methodological constraints weaken previous evidence on intra-articular viscosupplementation and physiological saline distention for osteoarthritis. We conducted a randomized, patient- and observer-blind trial to evaluate these interventions in patients with painful knee osteoarthritis.
Original languageEnglish
JournalScandinavian Journal of Rheumatology
Volume37
Issue number2
Pages (from-to)142-50
Number of pages9
ISSN0300-9742
DOIs
Publication statusPublished - 2008

Keywords

  • Adjuvants, Immunologic
  • Aged
  • Dose-Response Relationship, Drug
  • Drug Therapy, Combination
  • Female
  • Humans
  • Hyaluronic Acid
  • Injections, Intra-Articular
  • Male
  • Middle Aged
  • Osteoarthritis, Knee
  • Pain Measurement
  • Severity of Illness Index
  • Single-Blind Method
  • Sodium Chloride
  • Treatment Outcome

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