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The Capital Region of Denmark - a part of Copenhagen University Hospital
E-pub ahead of print

Interstitial lung abnormalities in people with HIV infection and uninfected controls

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BACKGROUND: Chest computed tomography (CT) findings in well-treated people with HIV infection (PWH) remain poorly characterized.

METHODS: A cross-sectional analysis examining interstitial chest CT findings in PWH (n=754) and uninfected controls (n=470).

RESULTS: HIV infection was independently associated with 1.82 (95%CI: 1.18-2.88) and 5.15 (95%CI: 1.72-22.2) higher adjusted odds of any interstitial lung abnormality and a finding suspicious for interstitial lung disease, respectively.

CONCLUSION: HIV infection was independently associated with interstitial lung abnormalities and findings suspicious for interstitial lung disease. Whether these abnormalities develop into more recognizable disease states over time is unknown but warrants further investigation.

Original languageEnglish
JournalThe Journal of infectious diseases
ISSN0022-1899
DOIs
Publication statusE-pub ahead of print - 31 Jan 2020

ID: 59245565