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International comparison of glycaemic control in people with type 1 diabetes: an update and extension

Research output: Contribution to journalJournal articlepeer-review

DOI

  1. Association of type 1 diabetes and educational achievement in 16-20-year-olds: A Danish nationwide register study

    Research output: Contribution to journalJournal articlepeer-review

  2. DBCG Kvalitetsdatabase for Brystkræft – resumé af årsrapport 2020

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  • R Prigge
  • J A McKnight
  • S H Wild
  • A Haynes
  • T W Jones
  • E A Davis
  • B Rami-Merhar
  • M Fritsch
  • Christine Prchla
  • A Lavens
  • K Doggen
  • S Chao
  • R Aronson
  • R Brown
  • E H Ibfelt
  • J Svensson
  • R Young
  • J T Warner
  • H Robinson
  • T Laatikainen
  • P Rautiainen
  • B Delemer
  • P F Souchon
  • A M Diallo
  • R W Holl
  • S M Schmid
  • K Raile
  • S Tigas
  • A Bargiota
  • I Zografou
  • A O Y Luk
  • J C N Chan
  • S F Dinneen
  • C M Buckley
  • O Kgosidialwa
  • V Cherubini
  • R Gesuita
  • I Strele
  • S Pildava
  • H Veeze
  • H-J Aanstoot
  • D Mul
  • Craig Jefferies
  • J G Cooper
  • K Fjeld Løvaas
  • T Battelino
  • K Dovc
  • N Bratina
  • K Eeg-Olofsson
  • A-M Svensson
  • Scottish Diabetes Research Network Epidemiology Group
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AIMS: To update and extend a previous cross-sectional international comparison of glycaemic control in people with type 1 diabetes.

METHODS: Data were obtained for 520,392 children and adults with type 1 diabetes from 17 population and five clinic-based data sources in countries or regions between 2016 and 2020. Median HbA1c (IQR) and proportions of individuals with HbA1c <58mmol/mol (<7.5%), 58 - 74 mmol/mol (7.5 - 8.9%) and ≥ 75 mmol/mol (≥ 9.0%) were compared between populations for individuals aged <15, 15 - 24 and ≥ 25years. Logistic regression was used to estimate the odds ratio (OR) of HbA1c < 58 mmol/mol (< 7.5%) relative to ≥ 58 mmol/mol (≥ 7.5%), stratified and adjusted for sex, age, and data source. Where possible, changes in the proportion of individuals in each HbA1c category compared to previous estimates were calculated.

RESULTS: Median HbA1c varied from 55 to 79 mmol/mol (7.2 to 9.4%) across data sources and age groups so a pooled estimate was deemed inappropriate. OR (95% CI) for HbA1c < 58 mmol/mol (<7.5 %) were 0.91 (0.90 - 0.92) for women compared to men, 1.68 (1.65 - 1.71) for people aged < 15 years and 0.81 (0.79 - 0.82) aged15 - 24 years compared to those aged ≥ 25 years. Differences between populations persisted after adjusting for sex, age, and data source. In general, compared to our previous analysis, the proportion of people with an HbA1c <58 mmol/l (<7.5%) increased and proportions of people with HbA1c ≥ 75 mmol/mol (≥ 9.0%) decreased.

CONCLUSIONS: Glycaemic control of type 1 diabetes continues to vary substantially between age groups and data sources. While some improvement over time has been observed, glycaemic control remains sub-optimal for most people with Type 1 diabetes.

Original languageEnglish
Article numbere14766
JournalDiabetic medicine : a journal of the British Diabetic Association
Volume39
Issue number5
Pages (from-to)e14766
ISSN0742-3071
DOIs
Publication statusPublished - 1 May 2022

Bibliographical note

This article is protected by copyright. All rights reserved.

    Research areas

  • HbA(1c), HbA1c, glycaemic control, registers of people with diabetes, type 1 diabetes

ID: 69767557