TY - JOUR
T1 - International comparison and time trends of first kidney transplant recipient characteristics across Europe
T2 - an ERA Registry study
AU - Boenink, Rianne
AU - Kramer, Anneke
AU - Masoud, Sherry
AU - Rodríguez-Benot, Alberto
AU - Helve, Jaakko
AU - Bistrup, Claus
AU - Segelmark, Mårten M
AU - Rodríguez Arévalo, Olga L
AU - Kerschbaum, Julia
AU - de Vries, Aiko P J
AU - Lundgren, Torbjörn
AU - Bell, Samira
AU - Crespo, Marta
AU - Sørensen, Søren S
AU - Ferraro, Pietro Manuel
AU - Arnol, Miha
AU - Bakkaloglu, Sevcan A
AU - Weekers, Laurent
AU - Reisæter, Anna Varberg
AU - Rebić, Damir
AU - Ortiz, Alberto
AU - Jager, Kitty J
AU - Stel, Vianda S
N1 - © The Author(s) 2023. Published by Oxford University Press on behalf of the ERA.
PY - 2024/4/1
Y1 - 2024/4/1
N2 - BACKGROUND: The aim of this study was to provide an overview of age, sex and primary renal disease (PRD) distribution among first kidney transplant recipients across Europe.METHOD: The European Renal Association (ERA) Registry database was used to obtain data on patients aged 20 years or older receiving their first kidney transplant between 2010 and 2019 from 12 European countries. The numbers and percentages of recipients in each age, sex and PRD group were calculated by country, donor type and year.RESULTS: In total, 99 543 adults received a first kidney transplant. Overall, 23% of the recipients were 65 years or older, 36% were female and 21% had glomerulonephritis and 15% diabetes mellitus as PRD. Compared with deceased donor kidney transplant recipients, living donor kidney transplant recipients were less often 65 years or older (13% versus 26%), more often had glomerulonephritis (25% versus 20%) and less often diabetes mellitus (8% versus 17%) as PRD. We found large international differences, which were most prominent for age and PRD and less prominent for sex. Over time, the largest change in recipient characteristics was observed for the percentage of recipients aged 65 years or older, increasing from 18% in 2010 to 28% in 2019 for all countries combined with a similar trend in most countries.CONCLUSION: We observed large differences for age and PRD distribution between recipients of living and deceased donor kidneys and between European countries. Over time, the percentage of older first kidney transplant recipients increased.
AB - BACKGROUND: The aim of this study was to provide an overview of age, sex and primary renal disease (PRD) distribution among first kidney transplant recipients across Europe.METHOD: The European Renal Association (ERA) Registry database was used to obtain data on patients aged 20 years or older receiving their first kidney transplant between 2010 and 2019 from 12 European countries. The numbers and percentages of recipients in each age, sex and PRD group were calculated by country, donor type and year.RESULTS: In total, 99 543 adults received a first kidney transplant. Overall, 23% of the recipients were 65 years or older, 36% were female and 21% had glomerulonephritis and 15% diabetes mellitus as PRD. Compared with deceased donor kidney transplant recipients, living donor kidney transplant recipients were less often 65 years or older (13% versus 26%), more often had glomerulonephritis (25% versus 20%) and less often diabetes mellitus (8% versus 17%) as PRD. We found large international differences, which were most prominent for age and PRD and less prominent for sex. Over time, the largest change in recipient characteristics was observed for the percentage of recipients aged 65 years or older, increasing from 18% in 2010 to 28% in 2019 for all countries combined with a similar trend in most countries.CONCLUSION: We observed large differences for age and PRD distribution between recipients of living and deceased donor kidneys and between European countries. Over time, the percentage of older first kidney transplant recipients increased.
KW - Adult
KW - Diabetes Mellitus
KW - Europe
KW - Female
KW - Glomerulonephritis
KW - Graft Survival
KW - Humans
KW - Kidney Diseases
KW - Kidney Transplantation
KW - Male
KW - Registries
KW - Tissue Donors
KW - Transplant Recipients
KW - kidney transplantation
KW - sex
KW - primary renal disease
KW - patient characteristics
KW - age
UR - http://www.scopus.com/inward/record.url?scp=85186561858&partnerID=8YFLogxK
U2 - 10.1093/ndt/gfad189
DO - 10.1093/ndt/gfad189
M3 - Journal article
C2 - 37653455
SN - 0931-0509
VL - 39
SP - 648
EP - 658
JO - Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
JF - Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
IS - 4
ER -