Interferon-γ inhibits ghrelin expression and secretion via a somatostatin-mediated mechanism

Jesper A B Strickertsson, Kristina B V Døssing, Anna JM Aabakke, Hans-Olof Nilsson, Thomas V O Hansen, Ulrich Knigge, Andreas Kjær, Torkel Wadström, Lennart Friis-Hansen

10 Citations (Scopus)

Abstract

To investigate if and how the proinflammatory cytokine interferon γ (IFNγ) affects ghrelin expression in mice.
Original languageEnglish
JournalWorld Journal of Gastroenterology
Volume17
Issue number26
Pages (from-to)3117-25
Number of pages9
ISSN1007-9327
DOIs
Publication statusPublished - 2011

Keywords

  • Animals
  • Cell Line
  • Female
  • Gastrins
  • Gastritis
  • Ghrelin
  • Helicobacter Infections
  • Helicobacter pylori
  • Histidine Decarboxylase
  • Humans
  • Interferon-gamma
  • Mice
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Promoter Regions, Genetic
  • Somatostatin
  • Stomach

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