Intake of ruminant trans fatty acids and risk of coronary heart disease-an overview

Marianne U Jakobsen; Anette Bysted; Niels Andersen; Berit L Heitmann; Henrik Bach Hartkopp; Torben Leth; Kim Overvad; Jørn Dyerberg

doi:10.1016/j.atherosclerosissup.2006.04.004

Intake of ruminant trans fatty acids and risk of coronary heart disease-an overview

Marianne U Jakobsen, Anette Bysted, Niels Andersen, Berit L Heitmann, Henrik Bach Hartkopp, Torben Leth, Kim Overvad, Jørn Dyerberg

44 Citations (Scopus)

Abstract

Epidemiological studies have shown a strong direct (positive) association between the intake of trans fatty acids (TFA) and the risk of coronary heart disease (CHD), primarily accounted for by industrially produced TFA (IP-TFA). However, comparisons between ruminant TFA (R-TFA) and IP-TFA and risk of CHD have been based on quintiles of intake, which implies that the associations between the two sources of TFA and the risk of CHD were described across different ranges of intake. Controlled metabolic studies of the effect of intake of total and specific R-TFA on CHD risk factors are warranted. Moreover, further epidemiological studies of intake of R-TFA and risk of CHD in populations with a high intake of R-TFA are warranted.

Original language	English
Journal	Atherosclerosis. Supplement
Volume	7
Issue number	2
Pages (from-to)	9-11
Number of pages	3
ISSN	1567-5688
DOIs	https://doi.org/10.1016/j.atherosclerosissup.2006.04.004
Publication status	Published - May 2006

Keywords

Animals
Case-Control Studies
Coronary Disease
Dietary Fats
Male
Risk Factors
Ruminants
Trans Fatty Acids

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10.1016/j.atherosclerosissup.2006.04.004

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title = "Intake of ruminant trans fatty acids and risk of coronary heart disease-an overview",

abstract = "Epidemiological studies have shown a strong direct (positive) association between the intake of trans fatty acids (TFA) and the risk of coronary heart disease (CHD), primarily accounted for by industrially produced TFA (IP-TFA). However, comparisons between ruminant TFA (R-TFA) and IP-TFA and risk of CHD have been based on quintiles of intake, which implies that the associations between the two sources of TFA and the risk of CHD were described across different ranges of intake. Controlled metabolic studies of the effect of intake of total and specific R-TFA on CHD risk factors are warranted. Moreover, further epidemiological studies of intake of R-TFA and risk of CHD in populations with a high intake of R-TFA are warranted.",

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AU - Jakobsen, Marianne U

AU - Bysted, Anette

AU - Andersen, Niels

AU - Heitmann, Berit L

AU - Hartkopp, Henrik Bach

AU - Leth, Torben

AU - Overvad, Kim

AU - Dyerberg, Jørn

PY - 2006/5

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N2 - Epidemiological studies have shown a strong direct (positive) association between the intake of trans fatty acids (TFA) and the risk of coronary heart disease (CHD), primarily accounted for by industrially produced TFA (IP-TFA). However, comparisons between ruminant TFA (R-TFA) and IP-TFA and risk of CHD have been based on quintiles of intake, which implies that the associations between the two sources of TFA and the risk of CHD were described across different ranges of intake. Controlled metabolic studies of the effect of intake of total and specific R-TFA on CHD risk factors are warranted. Moreover, further epidemiological studies of intake of R-TFA and risk of CHD in populations with a high intake of R-TFA are warranted.

AB - Epidemiological studies have shown a strong direct (positive) association between the intake of trans fatty acids (TFA) and the risk of coronary heart disease (CHD), primarily accounted for by industrially produced TFA (IP-TFA). However, comparisons between ruminant TFA (R-TFA) and IP-TFA and risk of CHD have been based on quintiles of intake, which implies that the associations between the two sources of TFA and the risk of CHD were described across different ranges of intake. Controlled metabolic studies of the effect of intake of total and specific R-TFA on CHD risk factors are warranted. Moreover, further epidemiological studies of intake of R-TFA and risk of CHD in populations with a high intake of R-TFA are warranted.

KW - Animals

KW - Case-Control Studies

KW - Coronary Disease

KW - Dietary Fats

KW - Male

KW - Risk Factors

KW - Ruminants

KW - Trans Fatty Acids

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JO - Atherosclerosis. Supplement

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IS - 2

ER -

Intake of ruminant trans fatty acids and risk of coronary heart disease-an overview

Abstract

Keywords

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