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Insufficient evidence in prophylactic therapy of chemotherapy-induced nausea and vomiting in children and adolescents

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Nausea and vomiting are burdensome side effects of chemotherapy. Vomiting is observed in up to 60% of treated children. An appropriate and effective antiemetic regimen has the potential to eradicate or reduce the symptoms. Differences in local guidelines characterise the antiemetic treatment across the four Danish paediatric oncology departments because the overall knowledge of the most effective antiemetics is incomplete. There is an unmet need for research, which can promote evidence-based guidelines. The impact of host genome polymorphisms should be included in the research.

Translated title of the contributionInsufficient evidence in prophylactic therapy of chemotherapy-induced nausea and vomiting in children and adolescents
Original languageDanish
JournalUgeskrift for Laeger
Volume180
Issue number35
Pages (from-to)V11170851
ISSN0041-5782
Publication statusPublished - 27 Aug 2018

ID: 55742367