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Insights on postneoadjuvant treatment among patients with triple-negative breast cancer and residual disease after neoadjuvant therapy: can expert consensus help to interpret the current evidence?

Antonis Valachis*, Jürgen Geisler, Peeter Karihtala, Malgorzata K. Tuxen

*Corresponding author for this work

Abstract

As treatment strategies for early triple-negative breast cancer continue to evolve, translating clinical evidence into practice can be challenging, especially as the standard of care also shifts and may differ across studies. The management of patients with triple-negative breast cancer who have residual disease after neoadjuvant therapy exemplifies a complex clinical scenario with emerging yet sometimes difficult-to-interpret evidence. Through a critical appraisal of current data and an expert consensus discussion from the Nordic region, the authors present a perspective on postneoadjuvant treatment options for triple-negative breast cancer and discuss potential approaches based on available evidence and expert opinion.

Original languageEnglish
JournalBritish Journal of Cancer
ISSN0007-0920
DOIs
Publication statusE-pub ahead of print - 29 Apr 2026

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