Influence of gender on EVAR outcomes with new low-profile devices

B L W Bendermacher, Nathalie Grootenboer, Ph W Cuypers, J A W Teijink, M R H M Van Sambeek

    14 Citations (Scopus)


    Women have not benefitted to the same extent as men of endovascular abdominal aortic repair (EVAR). Besides differences in hormones and the higher rate of undiagnosed cardiovascular disease, there are anatomical differences between men and women influencing the outcome of endovascular treatment of abdominal aortic aneurysms (AAA). After the first decade of EVAR procedures, only 28% of women with an elective AAA were treated by EVAR due to their poor anatomical suitability for this technique. The anatomical challenges and their associated poorer outcomes suggest the need for advances in device design to better meet the specific female aneurysm anatomy and physiology. Most of the newer-generation endografts have been associated with lower incidences of graft occlusion compared with first-generation endografts, and might be more suitable for women. It is encouraging that EVAR has decreased long-term mortality in women and that women's survival begins to equal men's after 2 years. However, detailed, adjusted anatomical data from population-based samples are needed for better understanding of the differences in AAA anatomy and EVAR eligibility. This information will contribute to enhance the design, testing and evaluation of future stent grafts, to ensure that women will benefit from EVAR to the same extent as men.
    Original languageEnglish
    JournalJournal of Cardiovascular Surgery
    Issue number5
    Pages (from-to)589-93
    Number of pages5
    Publication statusPublished - Oct 2013


    • Aortic Aneurysm, Abdominal
    • Blood Vessel Prosthesis
    • Blood Vessel Prosthesis Implantation
    • Endovascular Procedures
    • Female
    • Graft Occlusion, Vascular
    • Health Status Disparities
    • Healthcare Disparities
    • Hemodynamics
    • Humans
    • Male
    • Patient Selection
    • Prosthesis Design
    • Risk Factors
    • Sex Factors
    • Time Factors
    • Treatment Outcome


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