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Inflammatory cytokines and risk of coronary heart disease: new prospective study and updated meta-analysis

Stephen Kaptoge, Sreenivasa Rao Kondapally Seshasai, Pei Gao, Daniel F Freitag, Adam S Butterworth, Anders Borglykke, Emanuele Di Angelantonio, Vilmundur Gudnason, Ann Rumley, Gordon D O Lowe, Torben Jørgensen, John Danesh

    598 Citations (Scopus)

    Abstract

    Because low-grade inflammation may play a role in the pathogenesis of coronary heart disease (CHD), and pro-inflammatory cytokines govern inflammatory cascades, this study aimed to assess the associations of several pro-inflammatory cytokines and CHD risk in a new prospective study, including meta-analysis of prospective studies.
    Original languageEnglish
    JournalEuropean Heart Journal
    Volume35
    Issue number9
    Pages (from-to)578-589
    Number of pages11
    ISSN0195-668X
    DOIs
    Publication statusPublished - 2014

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