TY - JOUR
T1 - Infektiøs endokarditis
AU - Østergaard, Lauge
AU - Valeur, Nanna
AU - Tuxen, Christian Ditlev
AU - Bundgaard, Henning
AU - Iversen, Kasper
AU - Moser, Claus
AU - Helweg-Larsen, Jannik
AU - Smerup, Morten
AU - Bruun, Niels Eske
AU - Fosbøl, Emil
PY - 2022/3/21
Y1 - 2022/3/21
N2 - Infective endocarditis (IE) is one of the most severe infectious diseases with an in-hospital mortality of 20-25%. Several studies have shown, that the incidence of IE is increasing, and that patients now are older with a higher burden of comorbidities than previously. The diagnostic work-up is mainly based upon the presence of bacteraemia and echocardiography. The treatment is antibiotics and, in some cases, also cardiac surgery. In most cases, after clinical stabilization, it is safe to switch antibiotic treatment from intravenous to oral administration, as argued in this review.
AB - Infective endocarditis (IE) is one of the most severe infectious diseases with an in-hospital mortality of 20-25%. Several studies have shown, that the incidence of IE is increasing, and that patients now are older with a higher burden of comorbidities than previously. The diagnostic work-up is mainly based upon the presence of bacteraemia and echocardiography. The treatment is antibiotics and, in some cases, also cardiac surgery. In most cases, after clinical stabilization, it is safe to switch antibiotic treatment from intravenous to oral administration, as argued in this review.
KW - Administration, Oral
KW - Anti-Bacterial Agents/therapeutic use
KW - Bacteremia/drug therapy
KW - Endocarditis/diagnostic imaging
KW - Endocarditis, Bacterial/diagnostic imaging
KW - Humans
M3 - Review
C2 - 35319455
VL - 184
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 12
ER -