Indikation for tyroxinbehandling efter operation for ikkeendemisk atoksisk struma

H L Kristensen; U F Feldt-Rasmussen; M Blichert-Toft

Indikation for tyroxinbehandling efter operation for ikkeendemisk atoksisk struma

Translated title of the contribution: Indication for thyrotoxine therapy after surgery of non-endemic non-toxic goiter

H L Kristensen, U F Feldt-Rasmussen, M Blichert-Toft

2 Citations (Scopus)

Abstract

Levo-thyroxine has for many years been used after operation for non-toxic goitre to prevent recurrence and postoperative thyroid hypofunction. The philosophy behind prevention was to suppress production of the thyroid stimulating hormone (TSH), which was assumed to be the main growth factor for the thyroid gland. Suppression of the serum-TSH concentration by thyroxine therefore seemed logical. No scientific documentation verifying this assumption has been found in non-endemic goitre areas. Treatment with levo-thyroxine subsequent to goitre surgery is thus only indicated in situations with risk of hypofunction, viz. when only a small thyroid remnant is left.

Translated title of the contribution	Indication for thyrotoxine therapy after surgery of non-endemic non-toxic goiter
Original language	Danish
Journal	Ugeskrift for Laeger
Volume	157
Issue number	17
Pages (from-to)	2423-6
Number of pages	4
ISSN	0041-5782
Publication status	Published - 24 Apr 1995
Externally published	Yes

Cite this

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title = "Indikation for tyroxinbehandling efter operation for ikkeendemisk atoksisk struma",

abstract = "Levo-thyroxine has for many years been used after operation for non-toxic goitre to prevent recurrence and postoperative thyroid hypofunction. The philosophy behind prevention was to suppress production of the thyroid stimulating hormone (TSH), which was assumed to be the main growth factor for the thyroid gland. Suppression of the serum-TSH concentration by thyroxine therefore seemed logical. No scientific documentation verifying this assumption has been found in non-endemic goitre areas. Treatment with levo-thyroxine subsequent to goitre surgery is thus only indicated in situations with risk of hypofunction, viz. when only a small thyroid remnant is left.",

keywords = "Goiter/surgery, Humans, Postoperative Care, Recurrence, Thyroxine/therapeutic use",

author = "Kristensen, \{H L\} and Feldt-Rasmussen, \{U F\} and M Blichert-Toft",

year = "1995",

month = apr,

day = "24",

language = "Dansk",

volume = "157",

pages = "2423--6",

journal = "Ugeskrift for Laeger",

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TY - JOUR

T1 - Indikation for tyroxinbehandling efter operation for ikkeendemisk atoksisk struma

AU - Kristensen, H L

AU - Feldt-Rasmussen, U F

AU - Blichert-Toft, M

PY - 1995/4/24

Y1 - 1995/4/24

N2 - Levo-thyroxine has for many years been used after operation for non-toxic goitre to prevent recurrence and postoperative thyroid hypofunction. The philosophy behind prevention was to suppress production of the thyroid stimulating hormone (TSH), which was assumed to be the main growth factor for the thyroid gland. Suppression of the serum-TSH concentration by thyroxine therefore seemed logical. No scientific documentation verifying this assumption has been found in non-endemic goitre areas. Treatment with levo-thyroxine subsequent to goitre surgery is thus only indicated in situations with risk of hypofunction, viz. when only a small thyroid remnant is left.

AB - Levo-thyroxine has for many years been used after operation for non-toxic goitre to prevent recurrence and postoperative thyroid hypofunction. The philosophy behind prevention was to suppress production of the thyroid stimulating hormone (TSH), which was assumed to be the main growth factor for the thyroid gland. Suppression of the serum-TSH concentration by thyroxine therefore seemed logical. No scientific documentation verifying this assumption has been found in non-endemic goitre areas. Treatment with levo-thyroxine subsequent to goitre surgery is thus only indicated in situations with risk of hypofunction, viz. when only a small thyroid remnant is left.

KW - Goiter/surgery

KW - Humans

KW - Postoperative Care

KW - Recurrence

KW - Thyroxine/therapeutic use

UR - https://www.scopus.com/pages/publications/0028954938

M3 - Review

C2 - 7762097

SN - 0041-5782

VL - 157

SP - 2423

EP - 2426

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 17

ER -

Indikation for tyroxinbehandling efter operation for ikkeendemisk atoksisk struma

Abstract

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