Increased serum concentration of G-CSF in cystic fibrosis patients with chronic Pseudomonas aeruginosa pneumonia

P Ø Jensen; C Moser; A Kharazmi; Tanja Pressler; C Koch; N Høiby

doi:10.1016/j.jcf.2005.12.004

Increased serum concentration of G-CSF in cystic fibrosis patients with chronic Pseudomonas aeruginosa pneumonia

P Ø Jensen, C Moser, A Kharazmi, Tanja Pressler, C Koch, N Høiby

34 Citations (Scopus)

Abstract

Chronic Pseudomonas aeruginosa lung infection is the major reason for premature death in patients with cystic fibrosis (CF). Infected patients experience a progressive deterioration of the lung tissue caused by a persistent accumulation of PMNs. We investigated if the pulmonary accumulation of PMNs is reflected as a migration of PMNs through the blood in chronically infected CF patients.

Original language	English
Journal	Journal of Cystic Fibrosis
Volume	5
Issue number	3
Pages (from-to)	145-51
Number of pages	7
ISSN	1569-1993
DOIs	https://doi.org/10.1016/j.jcf.2005.12.004
Publication status	Published - 1 Aug 2006

Keywords

Adolescent
Adult
Blood Cell Count
Cell Movement
Cystic Fibrosis
Female
Flow Cytometry
Granulocyte Colony-Stimulating Factor
Humans
Inflammation
Interleukin-8
Male
Middle Aged
Neutrophils
Pneumonia
Pseudomonas Infections
Tumor Necrosis Factor-alpha

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10.1016/j.jcf.2005.12.004

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title = "Increased serum concentration of G-CSF in cystic fibrosis patients with chronic Pseudomonas aeruginosa pneumonia",

abstract = "Chronic Pseudomonas aeruginosa lung infection is the major reason for premature death in patients with cystic fibrosis (CF). Infected patients experience a progressive deterioration of the lung tissue caused by a persistent accumulation of PMNs. We investigated if the pulmonary accumulation of PMNs is reflected as a migration of PMNs through the blood in chronically infected CF patients.",

keywords = "Adolescent, Adult, Blood Cell Count, Cell Movement, Cystic Fibrosis, Female, Flow Cytometry, Granulocyte Colony-Stimulating Factor, Humans, Inflammation, Interleukin-8, Male, Middle Aged, Neutrophils, Pneumonia, Pseudomonas Infections, Tumor Necrosis Factor-alpha",

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T1 - Increased serum concentration of G-CSF in cystic fibrosis patients with chronic Pseudomonas aeruginosa pneumonia

AU - Jensen, P Ø

AU - Moser, C

AU - Kharazmi, A

AU - Pressler, Tanja

AU - Koch, C

AU - Høiby, N

PY - 2006/8/1

Y1 - 2006/8/1

N2 - Chronic Pseudomonas aeruginosa lung infection is the major reason for premature death in patients with cystic fibrosis (CF). Infected patients experience a progressive deterioration of the lung tissue caused by a persistent accumulation of PMNs. We investigated if the pulmonary accumulation of PMNs is reflected as a migration of PMNs through the blood in chronically infected CF patients.

AB - Chronic Pseudomonas aeruginosa lung infection is the major reason for premature death in patients with cystic fibrosis (CF). Infected patients experience a progressive deterioration of the lung tissue caused by a persistent accumulation of PMNs. We investigated if the pulmonary accumulation of PMNs is reflected as a migration of PMNs through the blood in chronically infected CF patients.

KW - Adolescent

KW - Adult

KW - Blood Cell Count

KW - Cell Movement

KW - Cystic Fibrosis

KW - Female

KW - Flow Cytometry

KW - Granulocyte Colony-Stimulating Factor

KW - Humans

KW - Inflammation

KW - Interleukin-8

KW - Male

KW - Middle Aged

KW - Neutrophils

KW - Pneumonia

KW - Pseudomonas Infections

KW - Tumor Necrosis Factor-alpha

UR - https://www.scopus.com/pages/publications/33746161139

U2 - 10.1016/j.jcf.2005.12.004

DO - 10.1016/j.jcf.2005.12.004

M3 - Journal article

C2 - 16503423

SN - 1569-1993

VL - 5

SP - 145

EP - 151

JO - Journal of Cystic Fibrosis

JF - Journal of Cystic Fibrosis

IS - 3

ER -

Increased serum concentration of G-CSF in cystic fibrosis patients with chronic Pseudomonas aeruginosa pneumonia

Abstract

Keywords

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