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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Increased cocaine self-administration in M4 muscarinic acetylcholine receptor knockout mice

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  1. Correction to: Effects of glucagon-like peptide 1 analogs on alcohol intake in alcohol-preferring vervet monkeys

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  2. Three weeks of SSRI administration enhances the visual perceptual threshold - a randomized placebo-controlled study

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  3. Tryptophan depletion affects compulsive behaviour in rats: strain dependent effects and associated neuromechanisms

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  1. The effect of erythropoietin on electroconvulsive stimulation induced cognitive impairment in rats

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  2. Correction to: Effects of glucagon-like peptide 1 analogs on alcohol intake in alcohol-preferring vervet monkeys

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Inhibition of epileptiform activity by neuropeptide Y in brain tissue from drug-resistant temporal lobe epilepsy patients

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  4. Clinical association to FKBP5 rs1360780 in patients with depression

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The reinforcing effects of cocaine are mediated by the mesolimbic dopamine system. Behavioral and neurochemical studies have shown that the cholinergic muscarinic M(4) receptor subtype plays an important role in regulation of dopaminergic neurotransmission.
Original languageEnglish
JournalPsychopharmacology
Volume216
Issue number3
Pages (from-to)367-78
Number of pages12
ISSN0033-3158
DOIs
Publication statusPublished - 2011

    Research areas

  • Animals, Autoradiography, Behavior, Animal, Brain, Cocaine, Cocaine-Related Disorders, Conditioning, Operant, Dopamine, Dose-Response Relationship, Drug, Male, Mice, Mice, Knockout, Microdialysis, Motor Activity, Receptor, Muscarinic M4, Receptors, Dopamine D1, Receptors, Dopamine D2, Reinforcement Schedule, Self Administration

ID: 34672954