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Incorporation of 6-thioguanine nucleotides into DNA during maintenance therapy of childhood acute lymphoblastic leukemia-the influence of thiopurine methyltransferase genotypes

Maria Schou Ebbesen, Jacob Nersting, Jack H Jacobsen, Thomas L Frandsen, Kim Vettenranta, Jonas Abramsson, Finn Wesenberg, Kjeld Schmiegelow

35 Citations (Scopus)
Original languageEnglish
JournalJournal of Clinical Pharmacology
Volume53
Issue number6
Pages (from-to)670-4
Number of pages5
ISSN0091-2700
DOIs
Publication statusPublished - Jun 2013

Keywords

  • 6-Mercaptopurine
  • Antineoplastic Combined Chemotherapy Protocols
  • Child
  • DNA
  • Female
  • Genotype
  • Guanine Nucleotides
  • Humans
  • Male
  • Methotrexate
  • Methyltransferases
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Thionucleotides

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