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Incidence, prevalence and risk factors for hepatitis C in Danish prisons

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Harvard

Søholm, J, Holm, DK, Mössner, B, Madsen, LW, Hansen, JF, Weis, N, Sauer, AP, Awad, T & Christensen, PB 2019, 'Incidence, prevalence and risk factors for hepatitis C in Danish prisons' PLoS One, vol. 14, no. 7, e0220297. https://doi.org/10.1371/journal.pone.0220297

APA

Søholm, J., Holm, D. K., Mössner, B., Madsen, L. W., Hansen, J. F., Weis, N., ... Christensen, P. B. (2019). Incidence, prevalence and risk factors for hepatitis C in Danish prisons. PLoS One, 14(7), [e0220297]. https://doi.org/10.1371/journal.pone.0220297

CBE

Søholm J, Holm DK, Mössner B, Madsen LW, Hansen JF, Weis N, Sauer AP, Awad T, Christensen PB. 2019. Incidence, prevalence and risk factors for hepatitis C in Danish prisons. PLoS One. 14(7). https://doi.org/10.1371/journal.pone.0220297

MLA

Vancouver

Søholm J, Holm DK, Mössner B, Madsen LW, Hansen JF, Weis N et al. Incidence, prevalence and risk factors for hepatitis C in Danish prisons. PLoS One. 2019 Jul 26;14(7). e0220297. https://doi.org/10.1371/journal.pone.0220297

Author

Søholm, Jacob ; Holm, Dorte Kinggaard ; Mössner, Belinda ; Madsen, Lone Wulff ; Hansen, Janne Fuglsang ; Weis, Nina ; Sauer, Agnes Pernille ; Awad, Tahany ; Christensen, Peer Brehm. / Incidence, prevalence and risk factors for hepatitis C in Danish prisons. In: PLoS One. 2019 ; Vol. 14, No. 7.

Bibtex

@article{9560dae19ddd4fedb45f5dee58bff2f7,
title = "Incidence, prevalence and risk factors for hepatitis C in Danish prisons",
abstract = "Hepatitis C virus (HCV) infection is prevalent among people in prison and prisons could therefore represent a unique opportunity to test risk groups for HCV. The aim of this sero-epidemiological study was to determine the incidence and prevalence of HCV infection and the corresponding risk factors in Danish prisons. Participants, recruited from eight Danish prisons, were tested for HCV using dried blood spots and filled out a questionaire with demographic data and risk factors for HCV infection. In total, 76.9{\%} (801/1041) of all eligible prisoners consented to participate. The prevalence of HCV RNA positive prisoners was 4.2{\%} (34/801) and the in-prison incidence rate was 0.7-1.0 per 100PY overall and 18-24/100PY among PWIDs. Infected prisoners were older than the overall population with a mean age of 42 years and only 17.6{\%} (6/34) were younger than 35 years. The prevalence of PWID was 8.5{\%} (68/801) and only 3{\%} (2/68) of PWID were younger than 25 years. Among the PWID, 85.3{\%} (58/68) had ever received opioid substitution therapy (OST) and 47.1{\%} (32/68) were currently receiving OST. Risk factors associated with HCV infection were intravenous drug use, age ≥ 40 years, and being incarcerated ≥ 10 years. In conclusion, the prevalence of PWID in Danish prisons is low, possibly reflecting a decrease in injecting among the younger generation. This together with OST coverage could explain the low prevalence of HCV infection. However among PWIDs in prison the incidence remains high, suggesting a need for improved HCV prevention in prison.",
author = "Jacob S{\o}holm and Holm, {Dorte Kinggaard} and Belinda M{\"o}ssner and Madsen, {Lone Wulff} and Hansen, {Janne Fuglsang} and Nina Weis and Sauer, {Agnes Pernille} and Tahany Awad and Christensen, {Peer Brehm}",
year = "2019",
month = "7",
day = "26",
doi = "10.1371/journal.pone.0220297",
language = "English",
volume = "14",
journal = "P L o S One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "7",

}

RIS

TY - JOUR

T1 - Incidence, prevalence and risk factors for hepatitis C in Danish prisons

AU - Søholm, Jacob

AU - Holm, Dorte Kinggaard

AU - Mössner, Belinda

AU - Madsen, Lone Wulff

AU - Hansen, Janne Fuglsang

AU - Weis, Nina

AU - Sauer, Agnes Pernille

AU - Awad, Tahany

AU - Christensen, Peer Brehm

PY - 2019/7/26

Y1 - 2019/7/26

N2 - Hepatitis C virus (HCV) infection is prevalent among people in prison and prisons could therefore represent a unique opportunity to test risk groups for HCV. The aim of this sero-epidemiological study was to determine the incidence and prevalence of HCV infection and the corresponding risk factors in Danish prisons. Participants, recruited from eight Danish prisons, were tested for HCV using dried blood spots and filled out a questionaire with demographic data and risk factors for HCV infection. In total, 76.9% (801/1041) of all eligible prisoners consented to participate. The prevalence of HCV RNA positive prisoners was 4.2% (34/801) and the in-prison incidence rate was 0.7-1.0 per 100PY overall and 18-24/100PY among PWIDs. Infected prisoners were older than the overall population with a mean age of 42 years and only 17.6% (6/34) were younger than 35 years. The prevalence of PWID was 8.5% (68/801) and only 3% (2/68) of PWID were younger than 25 years. Among the PWID, 85.3% (58/68) had ever received opioid substitution therapy (OST) and 47.1% (32/68) were currently receiving OST. Risk factors associated with HCV infection were intravenous drug use, age ≥ 40 years, and being incarcerated ≥ 10 years. In conclusion, the prevalence of PWID in Danish prisons is low, possibly reflecting a decrease in injecting among the younger generation. This together with OST coverage could explain the low prevalence of HCV infection. However among PWIDs in prison the incidence remains high, suggesting a need for improved HCV prevention in prison.

AB - Hepatitis C virus (HCV) infection is prevalent among people in prison and prisons could therefore represent a unique opportunity to test risk groups for HCV. The aim of this sero-epidemiological study was to determine the incidence and prevalence of HCV infection and the corresponding risk factors in Danish prisons. Participants, recruited from eight Danish prisons, were tested for HCV using dried blood spots and filled out a questionaire with demographic data and risk factors for HCV infection. In total, 76.9% (801/1041) of all eligible prisoners consented to participate. The prevalence of HCV RNA positive prisoners was 4.2% (34/801) and the in-prison incidence rate was 0.7-1.0 per 100PY overall and 18-24/100PY among PWIDs. Infected prisoners were older than the overall population with a mean age of 42 years and only 17.6% (6/34) were younger than 35 years. The prevalence of PWID was 8.5% (68/801) and only 3% (2/68) of PWID were younger than 25 years. Among the PWID, 85.3% (58/68) had ever received opioid substitution therapy (OST) and 47.1% (32/68) were currently receiving OST. Risk factors associated with HCV infection were intravenous drug use, age ≥ 40 years, and being incarcerated ≥ 10 years. In conclusion, the prevalence of PWID in Danish prisons is low, possibly reflecting a decrease in injecting among the younger generation. This together with OST coverage could explain the low prevalence of HCV infection. However among PWIDs in prison the incidence remains high, suggesting a need for improved HCV prevention in prison.

UR - http://www.scopus.com/inward/record.url?scp=85069958743&partnerID=8YFLogxK

U2 - 10.1371/journal.pone.0220297

DO - 10.1371/journal.pone.0220297

M3 - Journal article

VL - 14

JO - P L o S One

JF - P L o S One

SN - 1932-6203

IS - 7

M1 - e0220297

ER -

ID: 57713301