Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Incidence and Mortality of Cerebral Venous Thrombosis in a Norwegian Population

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Age At Menopause: A Female Risk Factor of Stroke?

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Tranexamic Acid for Prevention of Hematoma Expansion in Intracerebral Hemorrhage Patients With or Without Spot Sign

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Time to Thrombolysis and Long-Term Outcomes in Patients With Acute Ischemic Stroke: A Nationwide Study

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Cardiac Troponin I and Incident Stroke in European Cohorts: Insights From the BiomarCaRE Project

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Opening of BKCa channels causes migraine attacks: a new downstream target for the treatment of migraine

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Reference programme: diagnosis and treatment of headache disorders and facial pain. Danish Headache Society, 3rd edition, 2020

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Green Flags and headache: A concept study using the Delphi method

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Delayed headache after COVID-19 vaccination: a red flag for vaccine induced cerebral venous thrombosis

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. National Klinisk Retningslinje for ikke-medicinsk behandling af hovedpinesygdomme

    Research output: Contribution to journalJournal articleCommunication

  • Espen Saxhaug Kristoffersen
  • Charlotte Elena Harper
  • Kjersti Grøtta Vetvik
  • Svetozar Zarnovicky
  • Jakob Møller Hansen
  • Kashif Waqar Faiz
View graph of relations

BACKGROUND AND PURPOSE: There are conflicting figures of the incidence of cerebral venous thrombosis (CVT). The incidence was previously estimated to around 0.5/100 000/y, but more recent studies have suggested 1 to 1.5/100 000/y. The purpose of this study was to explore the incidence and mortality of CVT in a Norwegian population.

METHODS: A retrospective cross-sectional hospital population-based study conducted at Akershus University Hospital serving roughly 10% of the total Norwegian population. Patients were identified through chart reviews based on the relevant International Classification of Diseases(Tenth Revision) codes for new CVT cases in a 7-year period between January 1, 2011, and December 31, 2017. Only inhabitants living in the hospital's catchment area were included.

RESULTS: Sixty-two patients aged 0 to 80 years were identified and included. The median age was 46 years and 53% were females. The overall incidence of CVT was 1.75 (95% CI, 1.36-2.23) per 100 000/y with no significant sex differences. The incidence for children and adolescents (<18 years, n=9) was lower than for adults (≥18 years, n=53); 1.08 (0.52-1.97) versus 1.96 (1.49-2.55) per 100 000/y per year, with the highest incidence for those >50 years with 2.10 (1.38-3.07)/100 000/y. Headache was the most prevalent symptom, reported in 83%, followed by nausea, motor deficits, and seizures observed in 45%, 32%, and 32% of the patients. Transverse sinuses and the jugular vein were the most frequent sites of thrombosis. In most patients (61%), thrombosis occurred in multiple sinuses/veins. Risk factors were found in 73% of the patients, and most of the patients had a combination of 2 or more risk factors. The 30-day and 1-year mortality rates were 3% and 6%.

CONCLUSIONS: The incidence of CVT in this population was higher than previously reported. The mortality rate was similar to previous studies.

Original languageEnglish
JournalStroke
Volume51
Issue number10
Pages (from-to)3023-3029
Number of pages7
ISSN0039-2499
DOIs
Publication statusPublished - 2020

    Research areas

  • Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Cross-Sectional Studies, Female, Humans, Incidence, Infant, Infant, Newborn, Intracranial Thrombosis/epidemiology, Male, Middle Aged, Norway/epidemiology, Retrospective Studies, Survival Rate, Venous Thrombosis/epidemiology, Young Adult, seizure, thrombosis, risk factors, population, mortality, headache

ID: 61821989