Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

In vivo 1H spectroscopy of the human brain at 1.5 tesla. Preliminary experience at a clinical installation.

Research output: Contribution to journalJournal articleResearch

  1. Grading lumbar disc degeneration: a comparison between low- and high-field MRI

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. New Section Editor: Chest Imaging

    Research output: Contribution to journalJournal articleCommunication

  3. New section editor: Abdominal and Gastrointestinal Radiology

    Research output: Contribution to journalJournal articleCommunication

  4. New MSK editor

    Research output: Contribution to journalJournal articleCommunication

  • O Henriksen
  • H Larsson
  • K M Jensen
View graph of relations
In vivo localized water suppressed proton spectroscopy of human brain was carried out on 15 healthy volunteers and 2 patients suffering from a brain tumour and an infarction, respectively. The measurements were performed on a whole body MR system, operating at 1.5 tesla using the stimulated echo technique. Our preliminary results indicate that it is possible to detect a number of metabolites in the brain within a total measurement time of one hour. The dominant peaks in the spectra from healthy volunteers are N-acetyl aspartate, choline and creatine/phosphocreatine. The spectra obtained from the brain tumour and the infarct, respectively, differed very much from those obtained in healthy brain tissue. Our preliminary results indicate that localized proton spectroscopy may contribute to non-invasive brain tumour classification and possibly also to the differentiation between tumours and infarcts in clinically doubtful cases.
Translated title of the contributionIn vivo 1H spectroscopy of the human brain at 1.5 tesla. Preliminary experience at a clinical installation.
Original languageEnglish
JournalActa Radiologica
Volume31
Issue number2
Pages (from-to)181-186
Number of pages6
ISSN0284-1851
Publication statusPublished - 1990

ID: 32570001