Improvement in renal function after everolimus introduction and calcineurin inhibitor reduction in maintenance thoracic transplant recipients: the significance of baseline glomerular filtration rate

Satish Arora; Einar Gude; Vilborg Sigurdardottir; Svend Aage Mortensen; Hans Eiskjær; Gerdt Riise; Lena Mared; Oystein Bjørtuft; Bjørn Ekmehag; Kjell Jansson; Svein Simonsen; Pål Aukrust; Dag Solbu; Martin Iversen; Lars Gullestad

doi:10.1016/j.healun.2011.12.010

Improvement in renal function after everolimus introduction and calcineurin inhibitor reduction in maintenance thoracic transplant recipients: the significance of baseline glomerular filtration rate

Satish Arora, Einar Gude, Vilborg Sigurdardottir, Svend Aage Mortensen, Hans Eiskjær, Gerdt Riise, Lena Mared, Oystein Bjørtuft, Bjørn Ekmehag, Kjell Jansson, Svein Simonsen, Pål Aukrust, Dag Solbu, Martin Iversen, Lars Gullestad

52 Citations (Scopus)

Abstract

The NOCTET (NOrdic Certican Trial in HEart and lung Transplantation) trial demonstrated that everolimus improves renal function in maintenance thoracic transplant (TTx) recipients. Nevertheless, introduction of everolimus is not recommended for patients with advanced renal failure. We evaluated NOCTET data to assess everolimus introduction amongst TTx recipients with advanced renal failure.

Original language	English
Journal	Journal of Heart and Lung Transplantation
Volume	31
Issue number	3
Pages (from-to)	259-65
Number of pages	7
ISSN	1053-2498
DOIs	https://doi.org/10.1016/j.healun.2011.12.010
Publication status	Published - 2012

Keywords

Adaptor Proteins, Signal Transducing
Aged
Cyclosporine
Female
Follow-Up Studies
Glomerular Filtration Rate
Heart Transplantation
Humans
Immunosuppressive Agents
Kidney
Lung Transplantation
Male
Middle Aged
Postoperative Complications
Renal Insufficiency
Scandinavia
Sirolimus
Tacrolimus
Time Factors

Access to Document

10.1016/j.healun.2011.12.010

Cite this

Arora, S., Gude, E., Sigurdardottir, V., Mortensen, S. A., Eiskjær, H., Riise, G., Mared, L., Bjørtuft, O., Ekmehag, B., Jansson, K., Simonsen, S., Aukrust, P., Solbu, D., Iversen, M., & Gullestad, L. (2012). Improvement in renal function after everolimus introduction and calcineurin inhibitor reduction in maintenance thoracic transplant recipients: the significance of baseline glomerular filtration rate. Journal of Heart and Lung Transplantation, 31(3), 259-65. https://doi.org/10.1016/j.healun.2011.12.010

Improvement in renal function after everolimus introduction and calcineurin inhibitor reduction in maintenance thoracic transplant recipients: the significance of baseline glomerular filtration rate. / Arora, Satish; Gude, Einar; Sigurdardottir, Vilborg et al.
In: Journal of Heart and Lung Transplantation, Vol. 31, No. 3, 2012, p. 259-65.

Research output: Contribution to journal › Journal article › Research › peer-review

Arora, S, Gude, E, Sigurdardottir, V, Mortensen, SA, Eiskjær, H, Riise, G, Mared, L, Bjørtuft, O, Ekmehag, B, Jansson, K, Simonsen, S, Aukrust, P, Solbu, D, Iversen, M & Gullestad, L 2012, 'Improvement in renal function after everolimus introduction and calcineurin inhibitor reduction in maintenance thoracic transplant recipients: the significance of baseline glomerular filtration rate', Journal of Heart and Lung Transplantation, vol. 31, no. 3, pp. 259-65. https://doi.org/10.1016/j.healun.2011.12.010

Arora S, Gude E, Sigurdardottir V, Mortensen SA, Eiskjær H, Riise G et al. Improvement in renal function after everolimus introduction and calcineurin inhibitor reduction in maintenance thoracic transplant recipients: the significance of baseline glomerular filtration rate. Journal of Heart and Lung Transplantation. 2012;31(3):259-65. doi: 10.1016/j.healun.2011.12.010

@article{585289d3b2254ce28f9a2d970c95c78c,

title = "Improvement in renal function after everolimus introduction and calcineurin inhibitor reduction in maintenance thoracic transplant recipients: the significance of baseline glomerular filtration rate",

abstract = "The NOCTET (NOrdic Certican Trial in HEart and lung Transplantation) trial demonstrated that everolimus improves renal function in maintenance thoracic transplant (TTx) recipients. Nevertheless, introduction of everolimus is not recommended for patients with advanced renal failure. We evaluated NOCTET data to assess everolimus introduction amongst TTx recipients with advanced renal failure.",

keywords = "Adaptor Proteins, Signal Transducing, Aged, Cyclosporine, Female, Follow-Up Studies, Glomerular Filtration Rate, Heart Transplantation, Humans, Immunosuppressive Agents, Kidney, Lung Transplantation, Male, Middle Aged, Postoperative Complications, Renal Insufficiency, Scandinavia, Sirolimus, Tacrolimus, Time Factors",

author = "Satish Arora and Einar Gude and Vilborg Sigurdardottir and Mortensen, \{Svend Aage\} and Hans Eiskj{\ae}r and Gerdt Riise and Lena Mared and Oystein Bj{\o}rtuft and Bj{\o}rn Ekmehag and Kjell Jansson and Svein Simonsen and P{\aa}l Aukrust and Dag Solbu and Martin Iversen and Lars Gullestad",

year = "2012",

doi = "10.1016/j.healun.2011.12.010",

language = "English",

volume = "31",

pages = "259--65",

journal = "Journal of Heart and Lung Transplantation",

issn = "1053-2498",

publisher = "Elsevier Inc.",

number = "3",

}

TY - JOUR

T1 - Improvement in renal function after everolimus introduction and calcineurin inhibitor reduction in maintenance thoracic transplant recipients

T2 - the significance of baseline glomerular filtration rate

AU - Arora, Satish

AU - Gude, Einar

AU - Sigurdardottir, Vilborg

AU - Mortensen, Svend Aage

AU - Eiskjær, Hans

AU - Riise, Gerdt

AU - Mared, Lena

AU - Bjørtuft, Oystein

AU - Ekmehag, Bjørn

AU - Jansson, Kjell

AU - Simonsen, Svein

AU - Aukrust, Pål

AU - Solbu, Dag

AU - Iversen, Martin

AU - Gullestad, Lars

PY - 2012

Y1 - 2012

N2 - The NOCTET (NOrdic Certican Trial in HEart and lung Transplantation) trial demonstrated that everolimus improves renal function in maintenance thoracic transplant (TTx) recipients. Nevertheless, introduction of everolimus is not recommended for patients with advanced renal failure. We evaluated NOCTET data to assess everolimus introduction amongst TTx recipients with advanced renal failure.

AB - The NOCTET (NOrdic Certican Trial in HEart and lung Transplantation) trial demonstrated that everolimus improves renal function in maintenance thoracic transplant (TTx) recipients. Nevertheless, introduction of everolimus is not recommended for patients with advanced renal failure. We evaluated NOCTET data to assess everolimus introduction amongst TTx recipients with advanced renal failure.

KW - Adaptor Proteins, Signal Transducing

KW - Aged

KW - Cyclosporine

KW - Female

KW - Follow-Up Studies

KW - Glomerular Filtration Rate

KW - Heart Transplantation

KW - Humans

KW - Immunosuppressive Agents

KW - Kidney

KW - Lung Transplantation

KW - Male

KW - Middle Aged

KW - Postoperative Complications

KW - Renal Insufficiency

KW - Scandinavia

KW - Sirolimus

KW - Tacrolimus

KW - Time Factors

UR - https://www.scopus.com/pages/publications/84856872316

U2 - 10.1016/j.healun.2011.12.010

DO - 10.1016/j.healun.2011.12.010

M3 - Journal article

C2 - 22333403

SN - 1053-2498

VL - 31

SP - 259

EP - 265

JO - Journal of Heart and Lung Transplantation

JF - Journal of Heart and Lung Transplantation

IS - 3

ER -

Improvement in renal function after everolimus introduction and calcineurin inhibitor reduction in maintenance thoracic transplant recipients: the significance of baseline glomerular filtration rate

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this