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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Improved survival of head and neck cancer patients in Greenland

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  1. Gestational diabetes and macrosomia among Greenlanders. Time to change diagnostic strategy?

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  2. Gonorrhoea in Greenland: geographic differences in diagnostic activity and incidence of gonorrhoea in 2015

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  3. Validation of cardiovascular diagnoses in the Greenlandic Hospital Discharge Register for epidemiological use

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  4. Oncological treatment and outcome of colorectal cancer in Greenland

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  5. Increased incidence of gonorrhoea and chlamydia in Greenland 1990-2012

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  1. PET/CT prior to salvage surgery in recurrent head and neck squamous cell carcinoma

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  2. Comorbidity in HPV+ and HPV- oropharyngeal cancer patients: A population-based, case-control study

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  3. Intratumor heterogeneity of PD-L1 expression in head and neck squamous cell carcinoma

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Previously, head and neck cancer (HNC) patients in Greenland have had significant diagnostic delay and poor survival rates. From 2005-2009 several initiatives have been made to ensure faster diagnosis and better survival. The aim of this study was to compare the prognosis before and after these initiatives were introduced. All Greenlandic patients diagnosed with HNC between 2005 and 2012 were included. Data were retrieved from medical records and national databases and compared with the period 1994-2003. A total of 98 patients were identified. Diagnostic delay was significantly lower compared to the period 1994-2004 (p=0.048). The 3-year overall survival was 56% for all HNC and 47% for nasopharyngeal carcinomas. We found that patients with HNC between 1994 and 2003 had a higher risk of death from all reasons compared with the period 2005-2012 (HR 2.17; CI 1.46-3.23) after adjustments for stage and diagnostic delay. Patients with head HNC in Greenland from 2005-2012 were diagnosed earlier and had a better overall survival compared to the period 1994-2003. The change in survival is more likely to be due to improvement in treatment rather than the initiated interventions. Although survival has improved in Greenland, demographic problems and lack of specialists remain a challenge.

Original languageEnglish
JournalInternational Journal of Circumpolar Health
Volume77
Issue number1
Pages (from-to)1536252
ISSN1239-9736
DOIs
Publication statusPublished - 2018

ID: 56061008