Impotens forårsaget af behandling med methotrexat

Elisabeth I Penninga; Helle Kiellberg Larsen; Stig Ejdrup Andersen

Impotens forårsaget af behandling med methotrexat

Translated title of the contribution: Impotence caused by Methotrexate treatment

Elisabeth I Penninga
, Helle Kiellberg Larsen
, Stig Ejdrup Andersen

5 Citations (Scopus)

Abstract

Methotrexate (MTX) is used in the treatment of malignant and non-malignant diseases. This case report describes impotence as a seldom but possible overlooked adverse effect to MTX treatment. A 58 year-old man was treated for erythrodermia with a weekly dose of 7.5 mg MTX. He developed erective impotence nine months after initiation of treatment. Two weeks after discontinuation of MTX the impotence subsided, but when MTX treatment was reintroduced, the impotence returned after two months. Only a few other cases of impotence associated with MTX have been described previously.

Translated title of the contribution	Impotence caused by Methotrexate treatment
Original language	Danish
Journal	Ugeskrift for Laeger
Volume	170
Issue number	5
Pages (from-to)	354
ISSN	0041-5782
Publication status	Published - 28 Jan 2008

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title = "Impotens for{\aa}rsaget af behandling med methotrexat",

abstract = "Methotrexate (MTX) is used in the treatment of malignant and non-malignant diseases. This case report describes impotence as a seldom but possible overlooked adverse effect to MTX treatment. A 58 year-old man was treated for erythrodermia with a weekly dose of 7.5 mg MTX. He developed erective impotence nine months after initiation of treatment. Two weeks after discontinuation of MTX the impotence subsided, but when MTX treatment was reintroduced, the impotence returned after two months. Only a few other cases of impotence associated with MTX have been described previously.",

keywords = "Dermatitis, Exfoliative/drug therapy, Dermatologic Agents/adverse effects, Erectile Dysfunction/chemically induced, Humans, Male, Methotrexate/adverse effects, Middle Aged",

author = "Penninga, \{Elisabeth I\} and Larsen, \{Helle Kiellberg\} and Andersen, \{Stig Ejdrup\}",

year = "2008",

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language = "Dansk",

volume = "170",

pages = "354",

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T1 - Impotens forårsaget af behandling med methotrexat

AU - Penninga, Elisabeth I

AU - Larsen, Helle Kiellberg

AU - Andersen, Stig Ejdrup

PY - 2008/1/28

Y1 - 2008/1/28

N2 - Methotrexate (MTX) is used in the treatment of malignant and non-malignant diseases. This case report describes impotence as a seldom but possible overlooked adverse effect to MTX treatment. A 58 year-old man was treated for erythrodermia with a weekly dose of 7.5 mg MTX. He developed erective impotence nine months after initiation of treatment. Two weeks after discontinuation of MTX the impotence subsided, but when MTX treatment was reintroduced, the impotence returned after two months. Only a few other cases of impotence associated with MTX have been described previously.

AB - Methotrexate (MTX) is used in the treatment of malignant and non-malignant diseases. This case report describes impotence as a seldom but possible overlooked adverse effect to MTX treatment. A 58 year-old man was treated for erythrodermia with a weekly dose of 7.5 mg MTX. He developed erective impotence nine months after initiation of treatment. Two weeks after discontinuation of MTX the impotence subsided, but when MTX treatment was reintroduced, the impotence returned after two months. Only a few other cases of impotence associated with MTX have been described previously.

KW - Dermatitis, Exfoliative/drug therapy

KW - Dermatologic Agents/adverse effects

KW - Erectile Dysfunction/chemically induced

KW - Humans

KW - Male

KW - Methotrexate/adverse effects

KW - Middle Aged

M3 - Tidsskriftartikel

C2 - 18252170

SN - 0041-5782

VL - 170

SP - 354

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 5

ER -

Impotens forårsaget af behandling med methotrexat

Abstract

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