Implementing the number needed to harm in clinical practice: risk of myocardial infarction in HIV-1-infected patients treated with abacavir

Justyna Dominika Kowalska; O Kirk; A Mocroft; Line Weiland Høj; N Friis-Møller; P Reiss; I Weller; J D Lundgren

doi:10.1111/j.1468-1293.2009.00763.x

Implementing the number needed to harm in clinical practice: risk of myocardial infarction in HIV-1-infected patients treated with abacavir

Justyna Dominika Kowalska, O Kirk, A Mocroft, Line Weiland Høj, N Friis-Møller, P Reiss, I Weller, J D Lundgren

Department of Clinical Microbiology

14 Citations (Scopus)

Abstract

The D:A:D study group reported a 1.9-fold increased relative risk (RR) of myocardial infarction (MI) associated with current or recent use of abacavir. The number needed to harm (NNH) incorporates information about the underlying risk of MI and the increased RR of MI in patients taking abacavir.

Original language	English
Journal	Topics in HIV Medicine
Volume	11
Issue number	3
Pages (from-to)	200-8
Number of pages	9
ISSN	1542-8826
DOIs	https://doi.org/10.1111/j.1468-1293.2009.00763.x
Publication status	Published - 2010

Keywords

Adult
Age Factors
Aged
Blood Pressure
Cholesterol, HDL
Diabetes Mellitus
Dideoxynucleosides
HIV Infections
HIV-1
Humans
Male
Middle Aged
Models, Statistical
Myocardial Infarction
Randomized Controlled Trials as Topic
Reverse Transcriptase Inhibitors
Risk
Smoking
Uncertainty

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10.1111/j.1468-1293.2009.00763.x

Cite this

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title = "Implementing the number needed to harm in clinical practice: risk of myocardial infarction in HIV-1-infected patients treated with abacavir",

abstract = "The D:A:D study group reported a 1.9-fold increased relative risk (RR) of myocardial infarction (MI) associated with current or recent use of abacavir. The number needed to harm (NNH) incorporates information about the underlying risk of MI and the increased RR of MI in patients taking abacavir.",

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T1 - Implementing the number needed to harm in clinical practice

T2 - risk of myocardial infarction in HIV-1-infected patients treated with abacavir

AU - Kowalska, Justyna Dominika

AU - Kirk, O

AU - Mocroft, A

AU - Høj, Line Weiland

AU - Friis-Møller, N

AU - Reiss, P

AU - Weller, I

AU - Lundgren, J D

PY - 2010

Y1 - 2010

N2 - The D:A:D study group reported a 1.9-fold increased relative risk (RR) of myocardial infarction (MI) associated with current or recent use of abacavir. The number needed to harm (NNH) incorporates information about the underlying risk of MI and the increased RR of MI in patients taking abacavir.

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KW - Adult

KW - Age Factors

KW - Aged

KW - Blood Pressure

KW - Cholesterol, HDL

KW - Diabetes Mellitus

KW - Dideoxynucleosides

KW - HIV Infections

KW - HIV-1

KW - Humans

KW - Male

KW - Middle Aged

KW - Models, Statistical

KW - Myocardial Infarction

KW - Randomized Controlled Trials as Topic

KW - Reverse Transcriptase Inhibitors

KW - Risk

KW - Smoking

KW - Uncertainty

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DO - 10.1111/j.1468-1293.2009.00763.x

M3 - Journal article

C2 - 19863618

SN - 1542-8826

VL - 11

SP - 200

EP - 208

JO - Topics in HIV Medicine

JF - Topics in HIV Medicine

IS - 3

ER -

Implementing the number needed to harm in clinical practice: risk of myocardial infarction in HIV-1-infected patients treated with abacavir

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Keywords

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