Impact of system delay on infarct size, myocardial salvage index, and left ventricular function in patients with ST-segment elevation myocardial infarction

Jacob Lønborg; Mikkel Malby Schoos; Henning Kelbæk; Lene Holmvang; Jacob Steinmetz; Niels Vejlstrup; Erik Jørgensen; Steffen Helqvist; Kari Saunamäki; Hans Erik Bøtker; Won Yong Kim; Christian Juhl Terkelsen; Peter Clemmensen; Thomas Engstrøm

doi:10.1016/j.ahj.2012.07.021

Impact of system delay on infarct size, myocardial salvage index, and left ventricular function in patients with ST-segment elevation myocardial infarction

Jacob Lønborg, Mikkel Malby Schoos, Henning Kelbæk, Lene Holmvang, Jacob Steinmetz, Niels Vejlstrup, Erik Jørgensen, Steffen Helqvist, Kari Saunamäki, Hans Erik Bøtker, Won Yong Kim, Christian Juhl Terkelsen, Peter Clemmensen, Thomas Engstrøm

48 Citations (Scopus)

Abstract

The association between reperfusion delay and myocardial damage has previously been assessed by evaluation of the duration from symptom onset to invasive treatment, but results have been conflicting. System delay defined as the duration from first medical contact to first balloon dilatation is less prone to bias and is also modifiable. The purpose was to evaluate the impact of system delay on myocardial salvage index (MSI) and infarct size in patients with ST-elevation myocardial infarction treated with primary percutaneous coronary intervention (PCI).

Original language	English
Journal	American Heart Journal
Volume	164
Issue number	4
Pages (from-to)	538-46
Number of pages	9
ISSN	0002-8703
DOIs	https://doi.org/10.1016/j.ahj.2012.07.021
Publication status	Published - 2012

Keywords

Cardiotonic Agents
Coronary Occlusion
Female
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Myocardial Infarction
Myocardial Reperfusion
Myocardial Revascularization
Peptides
Regression Analysis
Time Factors
Venoms
Ventricular Function, Left

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10.1016/j.ahj.2012.07.021

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Lønborg, J., Schoos, M. M., Kelbæk, H., Holmvang, L., Steinmetz, J., Vejlstrup, N., Jørgensen, E., Helqvist, S., Saunamäki, K., Bøtker, H. E., Kim, W. Y., Terkelsen, C. J., Clemmensen, P., & Engstrøm, T. (2012). Impact of system delay on infarct size, myocardial salvage index, and left ventricular function in patients with ST-segment elevation myocardial infarction. American Heart Journal, 164(4), 538-46. https://doi.org/10.1016/j.ahj.2012.07.021

Impact of system delay on infarct size, myocardial salvage index, and left ventricular function in patients with ST-segment elevation myocardial infarction. / Lønborg, Jacob ; Schoos, Mikkel Malby; Kelbæk, Henning et al.
In: American Heart Journal, Vol. 164, No. 4, 2012, p. 538-46.

Research output: Contribution to journal › Journal article › Research › peer-review

Lønborg, J , Schoos, MM, Kelbæk, H, Holmvang, L , Steinmetz, J , Vejlstrup, N , Jørgensen, E , Helqvist, S, Saunamäki, K, Bøtker, HE, Kim, WY, Terkelsen, CJ, Clemmensen, P & Engstrøm, T 2012, 'Impact of system delay on infarct size, myocardial salvage index, and left ventricular function in patients with ST-segment elevation myocardial infarction', American Heart Journal, vol. 164, no. 4, pp. 538-46. https://doi.org/10.1016/j.ahj.2012.07.021

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abstract = "The association between reperfusion delay and myocardial damage has previously been assessed by evaluation of the duration from symptom onset to invasive treatment, but results have been conflicting. System delay defined as the duration from first medical contact to first balloon dilatation is less prone to bias and is also modifiable. The purpose was to evaluate the impact of system delay on myocardial salvage index (MSI) and infarct size in patients with ST-elevation myocardial infarction treated with primary percutaneous coronary intervention (PCI).",

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AU - Lønborg, Jacob

AU - Schoos, Mikkel Malby

AU - Kelbæk, Henning

AU - Holmvang, Lene

AU - Steinmetz, Jacob

AU - Vejlstrup, Niels

AU - Jørgensen, Erik

AU - Helqvist, Steffen

AU - Saunamäki, Kari

AU - Bøtker, Hans Erik

AU - Kim, Won Yong

AU - Terkelsen, Christian Juhl

AU - Clemmensen, Peter

AU - Engstrøm, Thomas

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AB - The association between reperfusion delay and myocardial damage has previously been assessed by evaluation of the duration from symptom onset to invasive treatment, but results have been conflicting. System delay defined as the duration from first medical contact to first balloon dilatation is less prone to bias and is also modifiable. The purpose was to evaluate the impact of system delay on myocardial salvage index (MSI) and infarct size in patients with ST-elevation myocardial infarction treated with primary percutaneous coronary intervention (PCI).

KW - Cardiotonic Agents

KW - Coronary Occlusion

KW - Female

KW - Humans

KW - Magnetic Resonance Imaging

KW - Male

KW - Middle Aged

KW - Myocardial Infarction

KW - Myocardial Reperfusion

KW - Myocardial Revascularization

KW - Peptides

KW - Regression Analysis

KW - Time Factors

KW - Venoms

KW - Ventricular Function, Left

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DO - 10.1016/j.ahj.2012.07.021

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JO - American Heart Journal

JF - American Heart Journal

IS - 4

ER -

Impact of system delay on infarct size, myocardial salvage index, and left ventricular function in patients with ST-segment elevation myocardial infarction

Abstract

Keywords

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