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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Impact of oral contraceptive use and menstrual phases on patellar tendon morphology, biochemical composition, and biomechanical properties in female athletes

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  1. Increased respiratory neural drive and work of breathing in exercise-induced laryngeal obstruction

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  2. Effects of anti-inflammatory (NSAID) treatment on human tendinopathic tissue

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  3. Effects of strict prolonged bed rest on cardiorespiratory fitness: systematic review and meta-analysis

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  4. Regulation of blood volume in lowlanders exposed to high altitude

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  5. CORP: The assessment of total hemoglobin mass by carbon monoxide rebreathing

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  1. Maintenance of muscle strength following a one-year resistance training program in older adults

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  2. Medication used in Denmark in the latent phase of labor - Do we know what we are doing?

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  3. The influence of prolonged strength training upon muscle and fat in healthy and chronically diseased older adults

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  4. Associations between shoulder symptoms and concomitant pathology in patients with traumatic supraspinatus tears

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  5. The effect of 4 months exercise training on systemic biomarkers of cartilage and bone turnover in hip osteoarthritis patients

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Sex differences exist with regards to ligament and tendon injuries. Lower collagen synthesis has been observed in exercising women vs. men, and in users of oral contraceptives (OC) vs. nonusers, but it is unknown if OC will influence tendon biomechanics of women undergoing regular training. Thirty female athletes (handball players, 18-30 yr) were recruited: 15 long-term users of OC (7.0 ± 0.6 yr) and 15 nonusers (>5 yr). Synchronized values of patellar tendon elongation (obtained by ultrasonography) and tendon force were sampled during ramped isometric knee extensor maximum voluntary contraction to estimate mechanical tendon properties. Furthermore, tendon cross-sectional area and length were measured from MRI images, and tendon biopsies were obtained for analysis of tendon fibril characteristics and collagen cross-linking. Overall, no difference in tendon biomechanical properties, tendon fibril characteristics, or collagen cross-linking was observed between the OC users and nonusers, or between the different phases of the menstrual cycle. In athletes, tendon cross-sectional area in the preferred jumping leg tended to be larger than that in the contralateral leg (P = 0.09), and a greater absolute (P = 0.01) and normalized tendon stiffness (P = 0.02), as well as a lower strain (P = 0.04), were observed in the jumping leg compared with the contralateral leg. The results indicate that long-term OC use or menstrual phases does not influence structure or mechanical properties of the patellar tendon in female team handball athletes.
Original languageEnglish
JournalJournal of applied physiology (Bethesda, Md. : 1985)
Volume114
Issue number8
Pages (from-to)998-1008
Number of pages11
ISSN8750-7587
DOIs
Publication statusPublished - Apr 2013

    Research areas

  • Adolescent, Adult, Analysis of Variance, Athletes, Biological Markers, Biomechanical Phenomena, Biopsy, Case-Control Studies, Collagen, Contraceptives, Oral, Cross-Sectional Studies, Exercise Test, Extracellular Matrix, Female, Humans, Isometric Contraction, Magnetic Resonance Imaging, Menstrual Cycle, Muscle, Skeletal, Patellar Ligament, Time Factors, Young Adult

ID: 42221094