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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Impact of congenital heart surgery on quality of life in children and adolescents with surgically corrected Ventricular Septal Defect, Tetralogy of Fallot, and Transposition of the Great Arteries

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  1. Activation delay-induced mechanical dyssynchrony in single-ventricle heart disease

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  2. Quality of life in adolescents and young adults with CHD is not reduced: a systematic review and meta-analysis

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  3. Absent right superior caval vein in situs solitus

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  4. Complete paroxysmal atrioventricular block in a 2-year-old girl

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  1. Association between transfusion of blood products and acute kidney injury following cardiac surgery

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  2. Fractional Flow Reserve Guided PCI in Patients With and Without Left Ventricular Hypertrophy: a DANAMI-3-PRIMULTI Sub-study

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  3. Intravascular Microaxial Left Ventricular Assist Device vs Intra-aortic Balloon Pump for Cardiogenic Shock

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OBJECTIVE: To describe the impact of CHD surgery in early childhood on quality of life in children aged 10-16 years with surgically corrected Ventricular Septal Defect, Transposition of the Great Arteries, and Tetralogy of Fallot.

METHOD: A cross-sectional survey study of quality of life survey on 161 children and adolescents aged 10-16 years with surgically corrected Ventricular Septal Defect, Transposition of the Great Arteries, and Tetralogy of Fallot. The international Paediatric Quality of Life 4.0 quality of life questionnaires were applied and collected for assessment from patients and parents. The endpoints were total, physical, emotional, social, and school quality of life scores.

RESULTS: The quality of life total and school scores was significantly lower in children with CHD than their healthy peers. There was no significant difference in quality of life between the three CHD groups. All three CHD groups had a significantly lower total (7.7-13.2%, p<0.001) and school scores (21.1-31.6%, p<0.001) than the control group. The tetralogy of Fallot group was the only group that had significantly lower scores in the physical subscale (p<0.001) than the controls.

CONCLUSION: Children and adolescents with surgically corrected CHD show losses in quality of life in total and school scores compared to healthy controls. The tetralogy of Fallot group was the only CHD group that had significantly lower physical score than the controls.

Original languageEnglish
JournalCardiology in the Young
Volume29
Issue number8
Pages (from-to)1082-1087
Number of pages6
ISSN1047-9511
DOIs
Publication statusPublished - 1 Aug 2019

    Research areas

  • CHD, Quality of life, questionnaire, Tetralogy of Fallot, Transposition of the Great Arteries, Ventricular Septal Defect

ID: 58442592