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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Immunological detection of the type V collagen propeptide fragment, PVCP-1230, in connective tissue remodeling associated with liver fibrosis

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  1. Pre-analytical and biological variability in circulating interleukin 6 in healthy subjects and patients with rheumatoid arthritis

    Research output: Contribution to journalJournal articleResearchpeer-review

  • Efstathios Vassiliadis
  • Sanne Skovgård Veidal
  • Henrik Simonsen
  • Dorthe Larsen
  • Ben Vainer
  • Xiaoliang Chen
  • Qinlong Zheng
  • Morten A Karsdal
  • Diana Julie Leeming
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Liver fibrosis involves excessive remodeling and deposition of fibrillar extracellular matrix (ECM) components, which leads to malfunction of the organ, causing significant morbidity and mortality. The aim of this study was to assess whether levels of a type V collagen fragment, the propeptide CO5-1230, indicate the amount of collagen deposited during liver fibrosis.
Original languageEnglish
JournalBiomarkers
Volume16
Issue number5
Pages (from-to)426-33
Number of pages8
ISSN1354-750X
DOIs
Publication statusPublished - 2011

    Research areas

  • Animals, Collagen Type V, Connective Tissue, Enzyme-Linked Immunosorbent Assay, Liver Cirrhosis, Male, Mice, Mice, Inbred BALB C, Peptide Fragments, Rats, Rats, Wistar, Reproducibility of Results

ID: 33229646