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Imaging in rheumatoid arthritis: the role of magnetic resonance imaging and computed tomography

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@article{41fe61d6365e4e4db98f005374335610,
title = "Imaging in rheumatoid arthritis: the role of magnetic resonance imaging and computed tomography",
abstract = "In suspected and diagnosed rheumatoid arthritis (RA), magnetic resonance imaging (MRI) allows detection of all relevant pathologies, such as synovitis, tenosynovitis, bone marrow edema (osteitis), bone erosion and cartilage damage. MRI is more sensitive than clinical examination for monitoring disease activity (i.e., inflammation) and more sensitive than conventional radiography and ultrasonography for monitoring joint destruction. In suspected RA, MRI bone marrow edema predicts development of RA, and in early RA patients, it predicts subsequent structural damage progression. CT is the standard reference imaging modality for visualizing bone damage, including bone erosions in RA, but lacks sensitivity for soft-tissue changes, including synovitis and tenosynovitis. CT has a minimal role in RA clinical trials and practice, except in selected patients where MRI is contraindicated or not available or if crystal arthritis such as gout or pseudo-gout is suspected. MRI has documented utility in diagnosis, monitoring and prognostication of patients with RA and is increasingly used for these purposes in clinical practice and particularly clinical trials.",
keywords = "Arthritis, Rheumatoid/diagnostic imaging, Diagnosis, Differential, Disease Progression, Humans, Magnetic Resonance Imaging/methods, Sensitivity and Specificity, Tomography, X-Ray Computed/methods",
author = "Mikkel {\O}stergaard and Mikael Boesen",
note = "COPECARE",
year = "2019",
month = "11",
doi = "10.1007/s11547-019-01014-y",
language = "English",
volume = "124",
pages = "1128--1141",
journal = "La Radiologia Medica",
issn = "0033-8362",
publisher = "Springer Italia Srl",
number = "11",

}

RIS

TY - JOUR

T1 - Imaging in rheumatoid arthritis

T2 - the role of magnetic resonance imaging and computed tomography

AU - Østergaard, Mikkel

AU - Boesen, Mikael

N1 - COPECARE

PY - 2019/11

Y1 - 2019/11

N2 - In suspected and diagnosed rheumatoid arthritis (RA), magnetic resonance imaging (MRI) allows detection of all relevant pathologies, such as synovitis, tenosynovitis, bone marrow edema (osteitis), bone erosion and cartilage damage. MRI is more sensitive than clinical examination for monitoring disease activity (i.e., inflammation) and more sensitive than conventional radiography and ultrasonography for monitoring joint destruction. In suspected RA, MRI bone marrow edema predicts development of RA, and in early RA patients, it predicts subsequent structural damage progression. CT is the standard reference imaging modality for visualizing bone damage, including bone erosions in RA, but lacks sensitivity for soft-tissue changes, including synovitis and tenosynovitis. CT has a minimal role in RA clinical trials and practice, except in selected patients where MRI is contraindicated or not available or if crystal arthritis such as gout or pseudo-gout is suspected. MRI has documented utility in diagnosis, monitoring and prognostication of patients with RA and is increasingly used for these purposes in clinical practice and particularly clinical trials.

AB - In suspected and diagnosed rheumatoid arthritis (RA), magnetic resonance imaging (MRI) allows detection of all relevant pathologies, such as synovitis, tenosynovitis, bone marrow edema (osteitis), bone erosion and cartilage damage. MRI is more sensitive than clinical examination for monitoring disease activity (i.e., inflammation) and more sensitive than conventional radiography and ultrasonography for monitoring joint destruction. In suspected RA, MRI bone marrow edema predicts development of RA, and in early RA patients, it predicts subsequent structural damage progression. CT is the standard reference imaging modality for visualizing bone damage, including bone erosions in RA, but lacks sensitivity for soft-tissue changes, including synovitis and tenosynovitis. CT has a minimal role in RA clinical trials and practice, except in selected patients where MRI is contraindicated or not available or if crystal arthritis such as gout or pseudo-gout is suspected. MRI has documented utility in diagnosis, monitoring and prognostication of patients with RA and is increasingly used for these purposes in clinical practice and particularly clinical trials.

KW - Arthritis, Rheumatoid/diagnostic imaging

KW - Diagnosis, Differential

KW - Disease Progression

KW - Humans

KW - Magnetic Resonance Imaging/methods

KW - Sensitivity and Specificity

KW - Tomography, X-Ray Computed/methods

U2 - 10.1007/s11547-019-01014-y

DO - 10.1007/s11547-019-01014-y

M3 - Review

VL - 124

SP - 1128

EP - 1141

JO - La Radiologia Medica

JF - La Radiologia Medica

SN - 0033-8362

IS - 11

ER -

ID: 58909567