IgG glycosylation changes and MBL2 polymorphisms: associations with markers of systemic inflammation and joint destruction in rheumatoid arthritis

Lone N Troelsen; Søren Jacobsen; Jodie L Abrahams; Louise Royle; Pauline M Rudd; Eva Narvestad; Niels Henrik Helweg Heegaard; Peter Garred

doi:10.3899/jrheum.110584

IgG glycosylation changes and MBL2 polymorphisms: associations with markers of systemic inflammation and joint destruction in rheumatoid arthritis

Lone N Troelsen
, Søren Jacobsen
, Jodie L Abrahams
, Louise Royle
, Pauline M Rudd
, Eva Narvestad
, Niels Henrik Helweg Heegaard
, Peter Garred

35 Citations (Scopus)

Abstract

To examine whether IgG glycosylation changes and MBL2 genotypes are associated with systemic inflammation and joint destruction in rheumatoid arthritis (RA).

Original language	English
Journal	Journal of Rheumatology
Volume	39
Issue number	3
Pages (from-to)	463-9
Number of pages	7
ISSN	0315-162X
DOIs	https://doi.org/10.3899/jrheum.110584
Publication status	Published - 2012

Keywords

Adult
Aged
Arthritis, Rheumatoid
Biological Markers
C-Reactive Protein
Cohort Studies
Female
Genotype
Homozygote
Humans
Immunoglobulin G
Inflammation
Interleukin-6
Joints
Male
Mannose-Binding Lectin
Middle Aged
Multivariate Analysis
Polymorphism, Genetic
Retrospective Studies
Tumor Necrosis Factor-alpha

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10.3899/jrheum.110584

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title = "IgG glycosylation changes and MBL2 polymorphisms: associations with markers of systemic inflammation and joint destruction in rheumatoid arthritis",

abstract = "To examine whether IgG glycosylation changes and MBL2 genotypes are associated with systemic inflammation and joint destruction in rheumatoid arthritis (RA).",

keywords = "Adult, Aged, Arthritis, Rheumatoid, Biological Markers, C-Reactive Protein, Cohort Studies, Female, Genotype, Homozygote, Humans, Immunoglobulin G, Inflammation, Interleukin-6, Joints, Male, Mannose-Binding Lectin, Middle Aged, Multivariate Analysis, Polymorphism, Genetic, Retrospective Studies, Tumor Necrosis Factor-alpha",

author = "Troelsen, \{Lone N\} and S{\o}ren Jacobsen and Abrahams, \{Jodie L\} and Louise Royle and Rudd, \{Pauline M\} and Eva Narvestad and Heegaard, \{Niels Henrik Helweg\} and Peter Garred",

year = "2012",

doi = "10.3899/jrheum.110584",

language = "English",

volume = "39",

pages = "463--9",

journal = "Journal of Rheumatology",

issn = "0315-162X",

publisher = "Journal of Rheumatology",

number = "3",

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TY - JOUR

T1 - IgG glycosylation changes and MBL2 polymorphisms

T2 - associations with markers of systemic inflammation and joint destruction in rheumatoid arthritis

AU - Troelsen, Lone N

AU - Jacobsen, Søren

AU - Abrahams, Jodie L

AU - Royle, Louise

AU - Rudd, Pauline M

AU - Narvestad, Eva

AU - Heegaard, Niels Henrik Helweg

AU - Garred, Peter

PY - 2012

Y1 - 2012

N2 - To examine whether IgG glycosylation changes and MBL2 genotypes are associated with systemic inflammation and joint destruction in rheumatoid arthritis (RA).

AB - To examine whether IgG glycosylation changes and MBL2 genotypes are associated with systemic inflammation and joint destruction in rheumatoid arthritis (RA).

KW - Adult

KW - Aged

KW - Arthritis, Rheumatoid

KW - Biological Markers

KW - C-Reactive Protein

KW - Cohort Studies

KW - Female

KW - Genotype

KW - Homozygote

KW - Humans

KW - Immunoglobulin G

KW - Inflammation

KW - Interleukin-6

KW - Joints

KW - Male

KW - Mannose-Binding Lectin

KW - Middle Aged

KW - Multivariate Analysis

KW - Polymorphism, Genetic

KW - Retrospective Studies

KW - Tumor Necrosis Factor-alpha

U2 - 10.3899/jrheum.110584

DO - 10.3899/jrheum.110584

M3 - Journal article

C2 - 22247351

SN - 0315-162X

VL - 39

SP - 463

EP - 469

JO - Journal of Rheumatology

JF - Journal of Rheumatology

IS - 3

ER -

IgG glycosylation changes and MBL2 polymorphisms: associations with markers of systemic inflammation and joint destruction in rheumatoid arthritis

Abstract

Keywords

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