IgE-mediated chlorhexidine allergy: a new occupational hazard?

Vasantha Nagendran; Jennifer Wicking; Anjali Ekbote; Theresa Onyekwe; Lene Heise Garvey

doi:10.1093/occmed/kqp042

IgE-mediated chlorhexidine allergy: a new occupational hazard?

Vasantha Nagendran, Jennifer Wicking, Anjali Ekbote, Theresa Onyekwe, Lene Heise Garvey

Dermatology and Allergy

70 Citations (Scopus)

Abstract

Chlorhexidine is an effective antimicrobial agent commonly used in UK hospitals, primarily for skin decontamination. Recent UK infection control guidelines recommend the use of 2% chlorhexidine solution in specific clinical settings, thus increasing chlorhexidine use by health care workers (HCWs). Chlorhexidine has been widely reported to cause IgE-mediated allergic reactions (from urticaria and angioedema to anaphylaxis) among patients undergoing surgery/invasive procedures. Despite its widespread use in health care settings, there are no reports of clinically confirmed occupational IgE-mediated chlorhexidine allergy.

Original language	English
Journal	Occupational Medicine
Volume	59
Issue number	4
Pages (from-to)	270-2
Number of pages	3
ISSN	0962-7480
DOIs	https://doi.org/10.1093/occmed/kqp042
Publication status	Published - 2009

Keywords

Adult
Anti-Infective Agents, Local
Chlorhexidine
Dermatitis, Occupational
Female
Great Britain
Hand Disinfection
Health Personnel
Hospitals, District
Humans
Hypersensitivity, Immediate
Immunoglobulin E
Infection Control
Male
Middle Aged
Questionnaires
Skin Tests

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10.1093/occmed/kqp042

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title = "IgE-mediated chlorhexidine allergy: a new occupational hazard?",

abstract = "Chlorhexidine is an effective antimicrobial agent commonly used in UK hospitals, primarily for skin decontamination. Recent UK infection control guidelines recommend the use of 2\% chlorhexidine solution in specific clinical settings, thus increasing chlorhexidine use by health care workers (HCWs). Chlorhexidine has been widely reported to cause IgE-mediated allergic reactions (from urticaria and angioedema to anaphylaxis) among patients undergoing surgery/invasive procedures. Despite its widespread use in health care settings, there are no reports of clinically confirmed occupational IgE-mediated chlorhexidine allergy.",

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author = "Vasantha Nagendran and Jennifer Wicking and Anjali Ekbote and Theresa Onyekwe and Garvey, \{Lene Heise\}",

year = "2009",

doi = "10.1093/occmed/kqp042",

language = "English",

volume = "59",

pages = "270--2",

journal = "Occupational Medicine",

issn = "0962-7480",

publisher = "Oxford University Press",

number = "4",

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TY - JOUR

T1 - IgE-mediated chlorhexidine allergy

T2 - a new occupational hazard?

AU - Nagendran, Vasantha

AU - Wicking, Jennifer

AU - Ekbote, Anjali

AU - Onyekwe, Theresa

AU - Garvey, Lene Heise

PY - 2009

Y1 - 2009

N2 - Chlorhexidine is an effective antimicrobial agent commonly used in UK hospitals, primarily for skin decontamination. Recent UK infection control guidelines recommend the use of 2% chlorhexidine solution in specific clinical settings, thus increasing chlorhexidine use by health care workers (HCWs). Chlorhexidine has been widely reported to cause IgE-mediated allergic reactions (from urticaria and angioedema to anaphylaxis) among patients undergoing surgery/invasive procedures. Despite its widespread use in health care settings, there are no reports of clinically confirmed occupational IgE-mediated chlorhexidine allergy.

AB - Chlorhexidine is an effective antimicrobial agent commonly used in UK hospitals, primarily for skin decontamination. Recent UK infection control guidelines recommend the use of 2% chlorhexidine solution in specific clinical settings, thus increasing chlorhexidine use by health care workers (HCWs). Chlorhexidine has been widely reported to cause IgE-mediated allergic reactions (from urticaria and angioedema to anaphylaxis) among patients undergoing surgery/invasive procedures. Despite its widespread use in health care settings, there are no reports of clinically confirmed occupational IgE-mediated chlorhexidine allergy.

KW - Adult

KW - Anti-Infective Agents, Local

KW - Chlorhexidine

KW - Dermatitis, Occupational

KW - Female

KW - Great Britain

KW - Hand Disinfection

KW - Health Personnel

KW - Hospitals, District

KW - Humans

KW - Hypersensitivity, Immediate

KW - Immunoglobulin E

KW - Infection Control

KW - Male

KW - Middle Aged

KW - Questionnaires

KW - Skin Tests

UR - https://www.scopus.com/pages/publications/66749089222

U2 - 10.1093/occmed/kqp042

DO - 10.1093/occmed/kqp042

M3 - Journal article

C2 - 19325161

SN - 0962-7480

VL - 59

SP - 270

EP - 272

JO - Occupational Medicine

JF - Occupational Medicine

IS - 4

ER -

IgE-mediated chlorhexidine allergy: a new occupational hazard?

Abstract

Keywords

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