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Identificering af nye ovariecancerbiomarkører med massespektrometriske proteomanalyser--fremtidens diagnostiske redskab?

Translated title of the contribution: Identification of new ovarian cancer biomarkers with proteomic analyses--the diagnostic tool of the future?

Anette Lykke Petri, Estrid Høgdall, Svend Aage Engelholm, Ib Jarle Christensen, Susanne Krüger Kjaer, Claus K Høgdall

Abstract

New non-invasive diagnostic tests for detection of ovarian cancer in early stages can improve survival. One approach is the proteomic analysis of serum or urine, which may be the technology needed. Preliminary proteomic analyses of serum and urine have shown a higher positive predictive value than that of the combination of serum CA125 and ultrasound examination, which actually is used preoperatively for the ovarian cancer diagnosis (RMI index). Identification of new ovarian cancer biomarkers will optimally be usable as an ovarian cancer-screening tool.

Translated title of the contributionIdentification of new ovarian cancer biomarkers with proteomic analyses--the diagnostic tool of the future?
Original languageDanish
JournalUgeskrift for Laeger
Volume169
Issue number33
Pages (from-to)2614-9
Number of pages6
ISSN0041-5782
Publication statusPublished - 13 Aug 2007
Externally publishedYes

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