Black holes (BHs), T1 hypointense lesions, are known predictors of multiple sclerosis disease severity, however, their identification is strongly intensity dependent. As traditional spin-echo T1 scans are being replaced by 3D gradient-echo images, we need to understand how hypointense lesions on these images compare. We assessed whether an intensity threshold for MPRAGE images exists that would allow to match spin-echo black hole definitions. Simple thresholding was only able to reproduce black hole segmentations to an intermediate degree.
Original languageEnglish
Publication date9 May 2022
Number of pages1
Publication statusPublished - 9 May 2022
EventJoint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting - London, Englnd, UK
Duration: 7 May 202212 May 2022


ConferenceJoint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting
LocationLondon, Englnd, UK
Internet address


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