Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Patch test results with fragrance markers of the baseline series - analysis of the European Surveillance System on Contact Allergies (ESSCA) network 2009-2012

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Quality of life and disease severity in dermatitis patients with fragrance allergy-A cross-sectional European questionnaire study

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Optimal patch test concentration for three widely used sensitizing fragrance substances without mandatory labelling in cosmetics

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Skin tape stripping: Which layers of the epidermis are removed?

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Highlights in allergic contact dermatitis 2018/2019

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Quality of life and disease severity in dermatitis patients with fragrance allergy-A cross-sectional European questionnaire study

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Optimal patch test concentration for three widely used sensitizing fragrance substances without mandatory labelling in cosmetics

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Skin tape stripping: Which layers of the epidermis are removed?

    Research output: Contribution to journalJournal articleResearchpeer-review

  • Peter J Frosch
  • Jeanne Duus Johansen
  • Marie-Louise A Schuttelaar
  • Juan F Silvestre
  • Javier Sánchez-Pérez
  • Elke Weisshaar
  • Wolfgang Uter
  • (on behalf of the ESSCA network)
View graph of relations

BACKGROUND: Contact allergy to fragrances is common, and impairs quality of life, particularly in young women.

OBJECTIVE: To provide current results on the prevalences of sensitization to fragrance allergens used as markers in the baseline series of most European countries.

METHODS: Data of patients consecutively patch tested between 2009 and 2012 in 12 European countries with fragrance allergens contained in the baseline series were collected by the European Surveillance System on Contact Allergies network and descriptively analysed. Four departments used the TRUE Test(®) system.

RESULTS: The 'basic markers' were tested on 51 477 [fragrance mix II (FM II)] to 57 123 [Myroxylon pereirae, balsam of Peru] patients, and yielded positive reactions as follows: fragrance mix I 6.9%, Myroxylon pereirae 5.4%, FM II 3.8%, colophonium 2.6%, and hydroxyisohexyl 3-cyclohexene carboxaldehyde 1.7%, with some regional differences. Prevalences with TRUE Test(®) allergens were lower. Additional fragrances were tested on 3643 (trimethylbenzenepropanol) to 14 071 (oil of turpentine) patients, and yielded between 2.6% (Cananga odorata) and 0.7% (trimethylbenzenepropanol) positive reactions.

CONCLUSIONS: Contact allergy to fragrances is common throughout Europe, with regional variation probably being explained by patch test technique, and differences in exposure and referral patterns. The current basic markers of fragrance sensitivity in the baseline series should be supplemented with additional fragrance allergens.

Original languageEnglish
JournalContact Dermatitis
Volume73
Issue number3
Pages (from-to)163-71
Number of pages9
ISSN0105-1873
DOIs
Publication statusPublished - Sep 2015

ID: 45624318