Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Exhaled CO, a predictor of lung function?

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Prognosis of COPD depends on severity of exacerbation history: A population-based analysis

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Spousal bereavement after fibrotic interstitial lung disease: A qualitative study

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Differentiation of adult severe asthma from difficult-to-treat asthma - Outcomes of a systematic assessment protocol

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Self-reported intake of fruit and vegetables and risk of chronic obstructive pulmonary disease: A nation-wide twin study

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Validation of ATS clinical practice guideline cut-points for FeNO in asthma

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Prognosis of COPD depends on severity of exacerbation history: A population-based analysis

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Metoclopramidinduceret respiratorisk dyskinesi

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Passiv rygning er en risikofaktor for udvikling af nedsat lungefunktion og KOL

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Automated oxygen control with O2matic® during admission with exacerbation of COPD

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations
BACKGROUND: Smoking is associated with an accelerated loss of lung function and inhalation accelerates the decline further. Exhaled CO reflects the exposure of smoke to the lungs. AIM: To investigate whether self-reported inhalation and type of cigarette influenced the level of exhaled CO and whether CO could provide additional information to usual measures of smoking regarding prediction of present lung function and decline in lung function over an extended period of time. METHOD: Cigarette smokers from the Copenhagen City Heart Study with valid measures of lung function and exhaled CO; in total 3738 subjects, 2096 women and 1642 men. RESULTS: Subjects not inhaling had slightly lower exhaled CO values than those inhaling, but substantially higher values than non-smokers (P<0.001). Smokers of plain cigarettes had slightly lower CO values than smokers of filter cigarettes (P<0.001). Increasing CO levels were correlated to a lower FEV(1)%pred and to an accelerated decline in lung function. However, in multiple linear regression analyses these correlations were not significant. CONCLUSION: Inhalation and type of cigarette affects exhaled CO levels. CO measures have no predictive value regarding neither present lung function nor decline in lung function with time in a population survey setting.
Original languageEnglish
JournalRespiratory medicine
Volume101
Issue number3
Pages (from-to)581-6
Number of pages6
ISSN0954-6111
DOIs
Publication statusPublished - 2007

    Research areas

  • Adult, Age Distribution, Aged, Breath Tests, Carbon Monoxide, Denmark, Female, Forced Expiratory Volume, Humans, Lung, Male, Middle Aged, Population Surveillance, Predictive Value of Tests, Prospective Studies, Sex Distribution, Smoking, Vital Capacity

ID: 32554783