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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Bilateral Diabetic Papillopathy and Metabolic Control

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OBJECTIVE: The pathogenesis of diabetic papillopathy largely is unknown, but case reports suggest that it may follow rapidly improved metabolic control. The present study was designed to investigate this hypothesis. DESIGN: Retrospective case-control study. PARTICIPANTS: Two thousand sixty-six patients with type 1 diabetes. METHODS: Review of clinical, photographic, and clinical chemistry records from a large diabetology and ophthalmology unit between 2001 and 2008. MAIN OUTCOME MEASURES: Simultaneous, bilateral diabetic papillopathy. RESULTS: The mean follow-up was 4.9 years. During 10 020 patient-years of observation, bilateral diabetic papillopathy developed in 5 patients. During the year preceding this incident, all 5 patients had experienced a decrease in glycosylated hemoglobin A(1c) (HbA(1C)) at a maximum rate of -2.5 (mean) percentage points per quarter year, which was significantly different from the changes in HbA(1C) observed in the remainder of the study population (P
Original languageEnglish
JournalOphthalmology
Volume117
Issue number11
Pages (from-to)214-217
Number of pages4
ISSN0161-6420
DOIs
Publication statusPublished - 15 Jun 2010

ID: 30974873