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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Stress og frugtbarhed. En forløbsundersøgelse blandt par, som forsøger at blive gravide for første gang

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  1. Perspektiver på recidiverende respiratorisk papillomatose og humant papillomvirus-vaccination

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  2. Balanced translocation in a patient with abortus habitualis and normal karyotype

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  3. The effect of antidepressants on brain volume

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  4. Nyt studie viser, at motion beskytter mod depression

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  5. Gentagne diploid biparental molae

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  1. A job-exposure matrix addressing hand exposure to wet work

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  2. High maternal age at first and subsequent child births in Denmark in the mid-1800s-Letter to the editor

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  3. Characterisation and localisation of the endocannabinoid system components in the adult human testis

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  4. Forebyggelse og behandling af cytomegalovirusinfektion hos gravide og nyfødte

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  5. Possible link between FSH and RANKL release from adipocytes in men with impaired gonadal function including Klinefelter syndrome

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Mental distress has often been suggested as a cause of unexplained infertility. However, the causal direction may well be from infertility to distress, and prospective data are needed. We therefore followed 393 couples, who were planning their first pregnancy, with prospective collection of information on distress from termination of birth control until pregnancy for a maximum of six menstrual cycles. The analyses included 1,475 menstrual cycles, and mental distress was measured in each cycle by the General Health Questionnaire (GHQ). Urine samples from each period of vaginal bleeding were analyzed for human chorionic gonadotrophic hormone, indicating early embryonal loss. We found that for cycles with the highest distress score (GHQ score above the 80 percentile) the probability of conception per cycle was 12.8% compared to 16.5% in other cycles (adjusted OR 0.6; 95% CI 0.4-1.0). The effect of distress was almost exclusively found among women with long menstrual cycles (OR 0.1; 95% CI 0.01-0.4 and OR 0.9; 0.5-1.4 for women with cycles > or = 35 and <35 days, respectively). An increased incidence of early embryonal loss was also found among highly distressed women with long cycles, but was based on a small number of observations. It is concluded that psychological distress may be a risk factor for reduced fertility in women with long menstrual cycles.
Translated title of the contributionStress and fertility. A follow-up study among couples planning the first pregnancy
Original languageDanish
JournalUgeskrift for Laeger
Volume162
Issue number38
Pages (from-to)5081-6
Number of pages6
ISSN0041-5782
Publication statusPublished - 18 Sep 2000

ID: 38730372