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The Capital Region of Denmark - a part of Copenhagen University Hospital
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An explorative analysis of ERCC1-19q13 copy number aberrations in a chemonaive stage III colorectal cancer cohort

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  1. Triage for selection to colonoscopy?

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  2. Diagnostic challenges in clinical, radiological and histopathological tests regarding papillomatous lesions of the breast

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  3. Clean Colorectum at Diagnostic Colonoscopy: Subsequent Detection of Extracolonic Malignancies by Plasma Protein Biomarkers?

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  4. Molecular prediction of adjuvant cisplatin efficacy in Non-Small Cell Lung Cancer (NSCLC)-validation in two independent cohorts

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Platinum-based chemotherapy has long been used in the treatment of a variety of cancers and functions by inducing DNA damage. ERCC1 and ERCC4 are involved in the removal of this damage and have previously been implicated in resistance to platinum compounds. The aim of the current investigation is to determine the presence, frequency and prognostic impact of ERCC1 or ERCC4 gene copy number alterations in colorectal cancer (CRC).
Original languageEnglish
JournalB M C Cancer
Volume13
Issue number1
Pages (from-to)489
ISSN1471-2407
DOIs
StatePublished - 21 Oct 2013

ID: 41767851