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Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia

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  • Giuseppe Saglio
  • Dong-Wook Kim
  • Surapol Issaragrisil
  • Philipp le Coutre
  • Gabriel Etienne
  • Clarisse Lobo
  • Ricardo Pasquini
  • Richard E Clark
  • Andreas Hochhaus
  • Timothy P Hughes
  • Neil Gallagher
  • Albert Hoenekopp
  • Mei Dong
  • Ariful Haque
  • Richard A Larson
  • Hagop M Kantarjian
  • ENESTnd Investigators
  • Ole Weis Bjerrum
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Nilotinib has been shown to be a more potent inhibitor of BCR-ABL than imatinib. We evaluated the efficacy and safety of nilotinib, as compared with imatinib, in patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia (CML) in the chronic phase.
Original languageEnglish
JournalNew England Journal of Medicine
Volume362
Issue number24
Pages (from-to)2251-9
Number of pages9
ISSN0028-4793
DOIs
Publication statusPublished - 17 Jun 2010

ID: 32244004